STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpen_0864Peptidase M50; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: pfu:PF0167 metalloprotease. (380 aa)    
Predicted Functional Partners:
uppS
Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
 
  
 0.896
Tpen_0863
Putative phage repressor; TIGRFAM: peptidase S26B, signal peptidase; PFAM: peptidase S24, S26A and S26B; KEGG: ape:APE1796 signal peptidase I.
 
  
 0.800
pyrH
Uridylate kinase, putative; Catalyzes the reversible phosphorylation of UMP to UDP.
 
  
 0.704
map
Methionine aminopeptidase, type II; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
  
  
 0.606
Tpen_0292
Putative phage repressor; TIGRFAM: peptidase S26B, signal peptidase; PFAM: peptidase S24, S26A and S26B; KEGG: ape:APE1796 signal peptidase I.
 
  
 0.586
hisS
KEGG: pab:PAB1100 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase, class II (G, H, P and S); Anticodon-binding domain protein; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
  
 0.577
Tpen_0141
PFAM: HhH-GPD family protein; SMART: iron-sulfur cluster loop; KEGG: sso:SSO0116 DNA endonuclease III, probable (ntH-1).
 
   
 0.537
Tpen_0494
PFAM: Fmu (Sun) domain protein; PUA domain containing protein; Methyltransferase type 11; KEGG: pab:PAB1173 proliferating-cell nucleolar antigen P120, putative.
 
  
 0.520
Tpen_0583
PFAM: Shwachman-Bodian-Diamond syndrome proteins; KEGG: pai:PAE2209 hypothetical protein.
  
     0.460
pelA
eRF1 domain 3 protein; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
 
     0.456
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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