STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpen_0906PFAM: extracellular solute-binding protein, family 3; SMART: ionotropic glutamate receptor; KEGG: pai:PAE2096 bacterial extracellular solute-binding proteins, family 3. (279 aa)    
Predicted Functional Partners:
Tpen_0905
TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ape:APE1892 putative polar amino acid transport system permease protein.
 0.999
Tpen_0904
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pai:PAE2001 glutamine transport ATP-binding.
 
 0.997
Tpen_0907
KEGG: ape:APE1894 hypothetical protein.
 
     0.617
Tpen_1466
PFAM: UspA domain protein; KEGG: sto:ST1524 hypothetical protein.
  
 
 0.497
Tpen_1058
TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein, family 1; KEGG: pfu:PF1003 phosphate-binding periplasmic protein precursor (pbp); Belongs to the PstS family.
  
  
 0.448
Tpen_1537
Threonine synthase-related protein; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: pto:PTO0564 pyridoxal-phosphate dependent enzyme.
     
 0.447
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
  
 0.416
Tpen_1089
PFAM: glutamine synthetase, catalytic region; KEGG: tko:TK1796 glutamine synthetase.
  
  
 0.408
gatD
glutamyl-tRNA(Gln) amidotransferase subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
  
  
 0.400
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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