STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpen_1027PFAM: phospholipase D/Transphosphatidylase; KEGG: tko:TK1563 phospholipase D-related protein. (184 aa)    
Predicted Functional Partners:
Tpen_1029
PFAM: AIR synthase related protein domain protein; KEGG: mta:Moth_0697 AIR synthase related protein-like.
  
    0.812
Tpen_1028
KEGG: ape:APE1194 hypothetical protein.
       0.773
tmk
PFAM: thymidylate kinase; KEGG: pfu:PF1730 dTMP kinase.
 
  
 0.680
Tpen_0080
Small GTP-binding protein; KEGG: ehi:95.t00027 Rab family GTPase; TIGRFAM: small GTP-binding protein; PFAM: Miro domain protein; Ras family protein; SMART: Ras small GTPase, Ras type; Ras small GTPase, Rho type; Ras small GTPase, Rab type.
   
 0.668
Tpen_0371
PFAM: protein of unknown function, ATP binding; KEGG: sso:SSO1046 hypothetical protein.
   
 0.668
Tpen_0585
PFAM: protein of unknown function, ATP binding; SMART: AAA ATPase; KEGG: pab:PAB0955 hypothetical protein.
   
 0.668
Tpen_0319
PFAM: peptidase M20; peptidase M28; KEGG: bld:BLi04074 YwaD.
    
 0.616
Tpen_1023
Rad51-like protein; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
     
 0.492
Tpen_1030
Ala-tRNA(Pro) hydrolase; PFAM: Threonyl/alanyl tRNA synthetase, SAD; KEGG: ape:APE0903 alanyl-tRNA synthetase.
       0.478
Tpen_1031
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: tma:TM1293 hypothetical protein.
  
  
 0.435
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.