STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpen_1069Phosphate uptake regulator, PhoU; TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein; PhoU family protein; KEGG: mac:MA0866 hypothetical protein. (340 aa)    
Predicted Functional Partners:
Tpen_1061
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: tko:TK1868 ABC-type phosphate transport system, ATPase component.
 
  
 0.892
Tpen_1060
TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ape:APE0048 phosphate transport system permease protein.
  
  
 0.870
Tpen_1058
TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein, family 1; KEGG: pfu:PF1003 phosphate-binding periplasmic protein precursor (pbp); Belongs to the PstS family.
  
  
 0.660
Tpen_0370
KEGG: ape:APE0784 hypothetical protein.
 
  
 0.651
ribK
Protein of unknown function DUF120; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
     0.635
Tpen_0943
Protein of unknown function DUF650, N-terminal domain; Involved in DNA damage repair.
 
     0.627
Tpen_1781
Protein of unknown function DUF650, N-terminal domain; Involved in DNA damage repair.
 
     0.599
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
  
     0.591
ef1b
Translation elongation factor 1B (aEF-1B); Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
  
     0.546
Tpen_0538
Transcriptional regulator, XRE family; PFAM: CBS domain containing protein; helix-turn-helix domain protein; KEGG: afu:AF2118 IMP dehydrogenase.
 
     0.487
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.