STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpen_1320TIGRFAM: CRISPR-associated RAMP protein, Cmr4 family; PFAM: protein of unknown function DUF324; KEGG: sso:SSO1726 hypothetical protein. (336 aa)    
Predicted Functional Partners:
Tpen_1317
TIGRFAM: CRISPR-associated RAMP protein, Cmr6 family; PFAM: protein of unknown function DUF324; KEGG: sso:SSO1990 hypothetical protein.
 
 
 
 0.987
Tpen_1316
KEGG: sso:SSO1991 hypothetical protein.
 
 
 
 0.983
Tpen_1315
KEGG: sto:ST1980 hypothetical protein.
   
 
 0.955
Tpen_1318
Hypothetical protein.
   
 
 0.949
Tpen_1319
TIGRFAM: CRISPR-associated protein, Cmr5 family; KEGG: sso:SSO1513 hypothetical protein.
       0.819
Tpen_1290
Metal dependent phosphohydrolase; KEGG: sto:ST0012 tRNA nucleotidyltransferase (CCA-adding enzyme); TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region.
   
 
 0.767
Tpen_1361
Hypothetical protein.
   
 
 0.767
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.646
Tpen_1354
CRISPR-associated helicase Cas3; KEGG: pfu:PF0640 ATP-dependent RNA helicase, putative; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like.
 
   
 0.536
Tpen_1342
TIGRFAM: putative CRISPR-associated protein, APE2256 family; KEGG: sso:SSO1393 hypothetical protein.
 
     0.457
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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