STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpen_1488TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase domain protein; biotin/lipoate A/B protein ligase; Helix-turn-helix, type 11 domain protein; KEGG: sth:STH1400 transcriptional repressor, BirA-like. (322 aa)    
Predicted Functional Partners:
Tpen_0119
Pyruvate carboxylase subunit A; PFAM: ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; RimK domain protein ATP-grasp; KEGG: mja:MJ1229 pyruvate carboxylase subunit A.
 0.994
Tpen_0156
PFAM: carboxyl transferase; KEGG: afu:AF2217 methylmalonyl-CoA decarboxylase alpha chain.
 
 
 0.984
Tpen_1491
PFAM: BioY protein; KEGG: afu:AF1169 biotin synthase.
 
   
 0.897
Tpen_1490
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mta:Moth_1456 ABC transporter related.
  
    0.806
Tpen_1489
Hypothetical protein.
       0.773
Tpen_1492
KEGG: sso:SSO2786 hypothetical protein.
       0.557
Tpen_0218
PFAM: CDP-alcohol phosphatidyltransferase; KEGG: pho:PH0460 CDPdiacylglycerol--glycerol-3-phsophate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
  
 0.531
Tpen_1251
Hypothetical protein; KEGG: sfu:Sfum_2923 CDP-alcohol phosphatidyltransferase.
  
  
 0.531
Tpen_1821
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pho:PH1901 3-oxoacyl-[acyl-carrier protein] reductase.
  
  
 0.524
Tpen_0915
KEGG: pab:PAB1763 hypothetical protein.
  
    0.479
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.