STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpen_1606PFAM: Rubrerythrin; Rubredoxin-type Fe(Cys)4 protein; KEGG: pab:PAB0598 rubrerythrin. (185 aa)    
Predicted Functional Partners:
Tpen_1570
1-Cys peroxiredoxin / 3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.757
Tpen_1830
PFAM: Desulfoferrodoxin, ferrous iron-binding region; KEGG: tte:TTE2229 putative superoxide reductase.
 
  
 0.685
Tpen_0503
PFAM: beta-lactamase domain protein; flavodoxin/nitric oxide synthase; KEGG: pab:PAB0596 flavoprotein.
 
  
 0.675
Tpen_1457
Rubredoxin-type Fe(Cys)4 protein; Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.
  
  
 0.673
Tpen_1655
KEGG: pfu:PF1192 hypothetical protein.
  
  
 0.668
Tpen_1605
PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: ape:APE1586 cysteine synthase.
     
 0.579
Tpen_1607
Hypothetical protein.
       0.563
Tpen_1604
SMART: ParB domain protein nuclease; KEGG: ape:APE0702 hypothetical protein.
       0.553
Tpen_1430
Redoxin domain protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sto:ST2102 hypothetical thioredoxin peroxidase.
     
 0.461
Tpen_0941
PFAM: beta-lactamase domain protein; KEGG: aae:aq_990 hypothetical protein.
  
  
 0.460
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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