STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpen_1772PFAM: THUMP domain protein; KEGG: ape:APE1156 hypothetical protein. (369 aa)    
Predicted Functional Partners:
tmcA
Protein of unknown function DUF699, ATPase putative; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
  
 0.883
truB
Putative rRNA pseudouridine synthase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
  
 
 0.701
Tpen_0379
PFAM: N2,N2-dimethylguanosine tRNA methyltransferase; conserved hypothetical protein 95; KEGG: pai:PAE1628 N2,N2-dimethylguonasine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
    
 
 0.667
nep1
Suppressor Mra1; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
  
  
 0.637
Tpen_1773
KEGG: sai:Saci_0236 hypothetical protein.
       0.628
Tpen_1774
KEGG: pai:PAE2285 hypothetical protein.
       0.628
Tpen_1771
KEGG: pai:PAE0826 hypothetical protein.
       0.620
Tpen_0884
PFAM: KH, type 1, domain protein; KEGG: pai:PAE1920 PhoH like protein.
  
     0.592
truD
Pseudouridylate synthase; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
   
   0.519
Tpen_0389
PFAM: Protein of unknown function DUF54; KEGG: ape:APE1451 hypothetical protein.
 
     0.516
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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