STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpen_1819PFAM: Methionine synthase, vitamin-B12 independent; KEGG: mka:MK0667 methionine synthase II (cobalamin-independent). (320 aa)    
Predicted Functional Partners:
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.985
Tpen_1605
PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: ape:APE1586 cysteine synthase.
  
 
 0.929
Tpen_0737
PFAM: S-adenosylmethionine synthetase (MAT); KEGG: ape:APE1596 S-adenosylmethionine synthetase.
     
 0.927
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
    
 0.916
Tpen_0611
L-threonine ammonia-lyase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: pai:PAE2316 threonine dehydratase.
  
 
 0.876
Tpen_1395
PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: aba:Acid345_2500 cysteine synthases.
  
 
 0.859
Tpen_1818
PFAM: sugar fermentation stimulation protein; KEGG: pfu:PF1198 sugar fermentation stimulation protein.
       0.779
Tpen_1820
TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region; Fe-S cluster domain protein; KEGG: pab:PAB2288 molybdopterin-guanine dinucleotide biosynthesis protein B.
       0.776
Tpen_1051
PFAM: GHMP kinase; GHMP kinase, C terminal domain protein; KEGG: mth:MTH577 hypothetical protein.
  
    0.773
Tpen_1821
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pho:PH1901 3-oxoacyl-[acyl-carrier protein] reductase.
     
 0.558
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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