STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpen_1822PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: mac:MA0255 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate synthesis protein ThiF. (256 aa)    
Predicted Functional Partners:
Tpen_0174
TIGRFAM: MoaD family protein; PFAM: thiamineS protein; KEGG: afu:AF2105 A. fulgidus predicted coding region AF2105.
  
 0.975
Tpen_0315
TIGRFAM: MoaD family protein; PFAM: thiamineS protein; KEGG: pai:PAE2580 hypothetical protein.
  
 0.975
rpl40e
PFAM: Ribosomal protein L40e; KEGG: pai:PAE3255 ribosomal protein L40; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.971
Tpen_0924
PFAM: thiamineS protein.
  
 
 0.964
Tpen_0314
PFAM: molybdopterin biosynthesis MoaE; KEGG: pai:PAE0727 molybdenum cofactor biosynthesis protein D/E.
  
 0.955
Tpen_0040
Glucose-inhibited division protein A; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; FAD dependent oxidoreductase; KEGG: pai:PAE1725 thioredoxin reductase.
  
  
 0.845
Tpen_1821
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pho:PH1901 3-oxoacyl-[acyl-carrier protein] reductase.
  
 
 0.832
flpA
rRNA 2'-O-methyltransferase fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
 
 
 0.828
cca
tRNA adenylyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
  
 
 0.778
Tpen_1820
TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region; Fe-S cluster domain protein; KEGG: pab:PAB2288 molybdopterin-guanine dinucleotide biosynthesis protein B.
  
  
 0.774
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.