SFI92794.1 protein (Terrisporobacter glycolicus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SFI92794.1

Peptide/nickel transport system permease protein. (314 aa)

Predicted Functional Partners:

SFI92814.1

0.990

SFI92831.1

0.986

SFJ19648.1

0.971

SFI92848.1

0.964

SFI92777.1

0.954

SFJ36001.1

0.953

SFJ19591.1

0.942

SFJ52064.1

0.932

SFJ36019.1

0.930

SFJ52014.1

0.923

Your Current Organism:

Terrisporobacter glycolicus

NCBI taxonomy Id: 36841
Other names: ATCC 14880, BCRC 14553, Clostridium glycolicum, Clostridium glycolinum, NCIMB 10632, NCTC 13026, T. glycolicus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFI92777.1	SFI92794.1	SAMN02910355_0157	SAMN02910355_0158	Peptide/nickel transport system substrate-binding protein.	Peptide/nickel transport system permease protein.	0.954
SFI92777.1	SFI92814.1	SAMN02910355_0157	SAMN02910355_0159	Peptide/nickel transport system substrate-binding protein.	Peptide/nickel transport system permease protein.	0.954
SFI92777.1	SFI92831.1	SAMN02910355_0157	SAMN02910355_0160	Peptide/nickel transport system substrate-binding protein.	Oligopeptide transport system ATP-binding protein; Belongs to the ABC transporter superfamily.	0.896
SFI92777.1	SFI92848.1	SAMN02910355_0157	SAMN02910355_0161	Peptide/nickel transport system substrate-binding protein.	Oligopeptide transport system ATP-binding protein; Belongs to the ABC transporter superfamily.	0.895
SFI92777.1	SFJ19591.1	SAMN02910355_0157	SAMN02910355_1478	Peptide/nickel transport system substrate-binding protein.	Oligopeptide transport system ATP-binding protein; Belongs to the ABC transporter superfamily.	0.727
SFI92777.1	SFJ19648.1	SAMN02910355_0157	SAMN02910355_1481	Peptide/nickel transport system substrate-binding protein.	Peptide/nickel transport system permease protein.	0.893
SFI92777.1	SFJ36001.1	SAMN02910355_0157	SAMN02910355_2421	Peptide/nickel transport system substrate-binding protein.	Oligopeptide transport system ATP-binding protein; Belongs to the ABC transporter superfamily.	0.733
SFI92777.1	SFJ36019.1	SAMN02910355_0157	SAMN02910355_2422	Peptide/nickel transport system substrate-binding protein.	Oligopeptide transport system permease protein.	0.855
SFI92777.1	SFJ52014.1	SAMN02910355_0157	SAMN02910355_2932	Peptide/nickel transport system substrate-binding protein.	Peptide/nickel transport system substrate-binding protein.	0.543
SFI92777.1	SFJ52064.1	SAMN02910355_0157	SAMN02910355_2935	Peptide/nickel transport system substrate-binding protein.	Peptide/nickel transport system permease protein.	0.894
SFI92794.1	SFI92777.1	SAMN02910355_0158	SAMN02910355_0157	Peptide/nickel transport system permease protein.	Peptide/nickel transport system substrate-binding protein.	0.954
SFI92794.1	SFI92814.1	SAMN02910355_0158	SAMN02910355_0159	Peptide/nickel transport system permease protein.	Peptide/nickel transport system permease protein.	0.990
SFI92794.1	SFI92831.1	SAMN02910355_0158	SAMN02910355_0160	Peptide/nickel transport system permease protein.	Oligopeptide transport system ATP-binding protein; Belongs to the ABC transporter superfamily.	0.986
SFI92794.1	SFI92848.1	SAMN02910355_0158	SAMN02910355_0161	Peptide/nickel transport system permease protein.	Oligopeptide transport system ATP-binding protein; Belongs to the ABC transporter superfamily.	0.964
SFI92794.1	SFJ19591.1	SAMN02910355_0158	SAMN02910355_1478	Peptide/nickel transport system permease protein.	Oligopeptide transport system ATP-binding protein; Belongs to the ABC transporter superfamily.	0.942
SFI92794.1	SFJ19648.1	SAMN02910355_0158	SAMN02910355_1481	Peptide/nickel transport system permease protein.	Peptide/nickel transport system permease protein.	0.971
SFI92794.1	SFJ36001.1	SAMN02910355_0158	SAMN02910355_2421	Peptide/nickel transport system permease protein.	Oligopeptide transport system ATP-binding protein; Belongs to the ABC transporter superfamily.	0.953
SFI92794.1	SFJ36019.1	SAMN02910355_0158	SAMN02910355_2422	Peptide/nickel transport system permease protein.	Oligopeptide transport system permease protein.	0.930
SFI92794.1	SFJ52014.1	SAMN02910355_0158	SAMN02910355_2932	Peptide/nickel transport system permease protein.	Peptide/nickel transport system substrate-binding protein.	0.923
SFI92794.1	SFJ52064.1	SAMN02910355_0158	SAMN02910355_2935	Peptide/nickel transport system permease protein.	Peptide/nickel transport system permease protein.	0.932

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

23

average node degree:

4.18

avg. local clustering coefficient:

0.828

expected number of edges:

12

PPI enrichment p-value:

0.00332

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009167

Purine ribonucleoside monophosphate metabolic process

5 of 41

2.17

3.21

2.48e-07

GO:0046033

AMP metabolic process

4 of 20

2.38

2.97

1.84e-06

GO:0006488

Dolichol-linked oligosaccharide biosynthetic process

4 of 22

2.34

2.94

1.96e-06

GO:0072522

Purine-containing compound biosynthetic process

5 of 105

1.76

2.24

6.38e-06

GO:0043101

Purine-containing compound salvage

3 of 13

2.45

2.21

6.92e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019205

Nucleobase-containing compound kinase activity

3 of 23

2.2

1.65

0.00072

GO:0016757

Glycosyltransferase activity

5 of 209

1.46

1.34

0.00052

GO:0016758

Hexosyltransferase activity

4 of 151

1.51

1.14

0.0027

GO:0004017

Adenylate kinase activity

2 of 7

2.54

1.12

0.0089

GO:0016740

Transferase activity

9 of 1618

0.83

0.7

0.00052

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:21503

UDP-N-acetylglucosamine transferase complex, and Protein of unknown function DUF6601

4 of 10

2.68

3.33

6.19e-07

CL:15640

Purine salvage

3 of 5

2.86

2.48

2.88e-05

CL:15463

Metabolism of nucleotides, and Nucleoside metabolic process

5 of 126

1.68

1.93

2.88e-05

CL:15601

Adenylate kinase/UMP-CMP kinase, and Uridine-diphosphatase activity

2 of 11

2.34

1.17

0.0070

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00513

Various types of N-glycan biosynthesis

4 of 69

1.85

2.09

2.93e-05

map00510

N-Glycan biosynthesis

4 of 74

1.81

2.06

2.93e-05

map00230

Purine metabolism

5 of 175

1.54

1.77

2.93e-05

map00730

Thiamine metabolism

2 of 44

1.74

0.86

0.0199

map01100

Metabolic pathways

10 of 3633

0.52

0.43

0.00077

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-74217

Purine salvage

3 of 7

2.71

2.5

2.46e-05

MAP-15869

Metabolism of nucleotides

5 of 111

1.74

2.04

2.00e-05

MAP-8956321

Nucleotide salvage

3 of 19

2.28

1.93

0.00021

MAP-9755088

Ribavirin ADME

2 of 7

2.54

1.24

0.0054

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0043541

UDP-N-acetylglucosamine transferase complex

4 of 6

2.91

3.91

6.12e-08

GOCC:0042406

Extrinsic component of endoplasmic reticulum membrane

4 of 7

2.84

3.89

6.12e-08

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13207

AAA domain

2 of 2

3.08

1.19

0.0071

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (18%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About