node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFJ15788.1 | SFJ15807.1 | SAMN02910355_1286 | SAMN02910355_1287 | Uncharacterized membrane protein. | Hypothetical protein. | 0.697 |
SFJ15788.1 | SFJ69871.1 | SAMN02910355_1286 | SAMN02910355_3762 | Uncharacterized membrane protein. | Uncharacterized membrane protein. | 0.561 |
SFJ15788.1 | SFJ70698.1 | SAMN02910355_1286 | SAMN02910355_3787 | Uncharacterized membrane protein. | Riboflavin transporter FmnP; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family. | 0.613 |
SFJ15788.1 | dltC | SAMN02910355_1286 | SAMN02910355_1473 | Uncharacterized membrane protein. | D-alanine--poly(phosphoribitol) ligase subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.409 |
SFJ15788.1 | nhaA | SAMN02910355_1286 | SAMN02910355_1285 | Uncharacterized membrane protein. | Na+:H+ antiporter, NhaA family; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. | 0.481 |
SFJ15788.1 | queA | SAMN02910355_1286 | SAMN02910355_3322 | Uncharacterized membrane protein. | S-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.687 |
SFJ15788.1 | tgt | SAMN02910355_1286 | SAMN02910355_3320 | Uncharacterized membrane protein. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.553 |
SFJ15807.1 | SFJ15788.1 | SAMN02910355_1287 | SAMN02910355_1286 | Hypothetical protein. | Uncharacterized membrane protein. | 0.697 |
SFJ15807.1 | nhaA | SAMN02910355_1287 | SAMN02910355_1285 | Hypothetical protein. | Na+:H+ antiporter, NhaA family; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. | 0.495 |
SFJ69871.1 | SFJ15788.1 | SAMN02910355_3762 | SAMN02910355_1286 | Uncharacterized membrane protein. | Uncharacterized membrane protein. | 0.561 |
SFJ69871.1 | SFJ70698.1 | SAMN02910355_3762 | SAMN02910355_3787 | Uncharacterized membrane protein. | Riboflavin transporter FmnP; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family. | 0.656 |
SFJ70698.1 | SFJ15788.1 | SAMN02910355_3787 | SAMN02910355_1286 | Riboflavin transporter FmnP; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family. | Uncharacterized membrane protein. | 0.613 |
SFJ70698.1 | SFJ69871.1 | SAMN02910355_3787 | SAMN02910355_3762 | Riboflavin transporter FmnP; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family. | Uncharacterized membrane protein. | 0.656 |
dltC | SFJ15788.1 | SAMN02910355_1473 | SAMN02910355_1286 | D-alanine--poly(phosphoribitol) ligase subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | Uncharacterized membrane protein. | 0.409 |
nhaA | SFJ15788.1 | SAMN02910355_1285 | SAMN02910355_1286 | Na+:H+ antiporter, NhaA family; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. | Uncharacterized membrane protein. | 0.481 |
nhaA | SFJ15807.1 | SAMN02910355_1285 | SAMN02910355_1287 | Na+:H+ antiporter, NhaA family; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. | Hypothetical protein. | 0.495 |
queA | SFJ15788.1 | SAMN02910355_3322 | SAMN02910355_1286 | S-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Uncharacterized membrane protein. | 0.687 |
queA | tgt | SAMN02910355_3322 | SAMN02910355_3320 | S-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.997 |
tgt | SFJ15788.1 | SAMN02910355_3320 | SAMN02910355_1286 | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | Uncharacterized membrane protein. | 0.553 |
tgt | queA | SAMN02910355_3320 | SAMN02910355_3322 | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | S-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.997 |