node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFJ68494.1 | SFJ68507.1 | SAMN02910355_3672 | SAMN02910355_3673 | RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family. | Serine/threonine-protein kinase RsbW. | 0.988 |
SFJ68494.1 | SFJ68525.1 | SAMN02910355_3672 | SAMN02910355_3674 | RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family. | Anti-sigma B factor antagonist; Belongs to the anti-sigma-factor antagonist family. | 0.989 |
SFJ68494.1 | SFJ68534.1 | SAMN02910355_3672 | SAMN02910355_3675 | RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family. | Protein of unknown function. | 0.705 |
SFJ68494.1 | SFJ68553.1 | SAMN02910355_3672 | SAMN02910355_3676 | RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family. | YtxH-like protein. | 0.707 |
SFJ68494.1 | SFJ68645.1 | SAMN02910355_3672 | SAMN02910355_3681 | RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family. | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.642 |
SFJ68494.1 | gyrA | SAMN02910355_3672 | SAMN02910355_3677 | RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.651 |
SFJ68494.1 | gyrB | SAMN02910355_3672 | SAMN02910355_3678 | RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.650 |
SFJ68494.1 | recF | SAMN02910355_3672 | SAMN02910355_3679 | RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.524 |
SFJ68494.1 | yaaA | SAMN02910355_3672 | SAMN02910355_3680 | RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family. | Ribosome-associated protein. | 0.506 |
SFJ68507.1 | SFJ68494.1 | SAMN02910355_3673 | SAMN02910355_3672 | Serine/threonine-protein kinase RsbW. | RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family. | 0.988 |
SFJ68507.1 | SFJ68525.1 | SAMN02910355_3673 | SAMN02910355_3674 | Serine/threonine-protein kinase RsbW. | Anti-sigma B factor antagonist; Belongs to the anti-sigma-factor antagonist family. | 0.999 |
SFJ68507.1 | SFJ68534.1 | SAMN02910355_3673 | SAMN02910355_3675 | Serine/threonine-protein kinase RsbW. | Protein of unknown function. | 0.705 |
SFJ68507.1 | SFJ68553.1 | SAMN02910355_3673 | SAMN02910355_3676 | Serine/threonine-protein kinase RsbW. | YtxH-like protein. | 0.718 |
SFJ68507.1 | SFJ68645.1 | SAMN02910355_3673 | SAMN02910355_3681 | Serine/threonine-protein kinase RsbW. | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.535 |
SFJ68507.1 | gyrA | SAMN02910355_3673 | SAMN02910355_3677 | Serine/threonine-protein kinase RsbW. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.577 |
SFJ68507.1 | gyrB | SAMN02910355_3673 | SAMN02910355_3678 | Serine/threonine-protein kinase RsbW. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.603 |
SFJ68507.1 | recF | SAMN02910355_3673 | SAMN02910355_3679 | Serine/threonine-protein kinase RsbW. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.546 |
SFJ68507.1 | yaaA | SAMN02910355_3673 | SAMN02910355_3680 | Serine/threonine-protein kinase RsbW. | Ribosome-associated protein. | 0.519 |
SFJ68525.1 | SFJ68494.1 | SAMN02910355_3674 | SAMN02910355_3672 | Anti-sigma B factor antagonist; Belongs to the anti-sigma-factor antagonist family. | RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family. | 0.989 |
SFJ68525.1 | SFJ68507.1 | SAMN02910355_3674 | SAMN02910355_3673 | Anti-sigma B factor antagonist; Belongs to the anti-sigma-factor antagonist family. | Serine/threonine-protein kinase RsbW. | 0.999 |