STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SKC62776.1Transcriptional pleiotropic regulator of transition state genes. (80 aa)    
Predicted Functional Partners:
SKC72316.1
Two-component system, response regulator, stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.805
spoIIAB
Stage II sporulation protein AB (anti-sigma F factor); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.745
SKC87333.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
     0.743
SKC56198.1
Putative DeoR family transcriptional regulator, stage III sporulation protein D.
  
   
 0.727
SKC72214.1
Stage III sporulation protein AC.
  
   
 0.698
SKC91495.1
Stage V sporulation protein AE.
  
     0.692
SKC87375.1
RNA polymerase, sigma 29 subunit, SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
    0.685
SKC91157.1
Sporulation protein YabP.
  
   
 0.685
SKC91488.1
Stage V sporulation protein AC.
  
     0.678
SKC87371.1
RNA polymerase, sigma subunit, RpsG/SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.676
Your Current Organism:
Maledivibacter halophilus
NCBI taxonomy Id: 36842
Other names: ATCC 49637, Clostridium halophilium, Clostridium halophilum, DSM 5387, M. halophilus, strain M1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.