STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFF65670.1DJ-1/PfpI family protein. (111 aa)    
Predicted Functional Partners:
SFF65658.1
Hypothetical protein.
       0.714
sigA_2
RNA polymerase primary sigma factor; Belongs to the sigma-70 factor family.
   
 
 0.696
sigA_1
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.696
SFF65638.1
Hypothetical protein.
       0.664
bdhA
Hypothetical protein.
  
    0.577
SFF64975.1
Nicotinamidase-related amidase.
  
    0.438
sttH
Nicotinamidase-related amidase.
  
    0.438
lexA_2
Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
   
   0.423
lexA_1
Repressor LexA.
   
   0.423
lexA_3
Peptidase S24-like; Belongs to the peptidase S24 family.
   
   0.423
Your Current Organism:
Clostridium homopropionicum
NCBI taxonomy Id: 36844
Other names: ATCC 51426, C. homopropionicum, DSM 5847, strain LuHBu1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.