STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoVAD_1Stage V sporulation protein AD. (338 aa)    
Predicted Functional Partners:
SFF97229.1
Stage V sporulation protein AC.
 
  
 0.978
SFF97298.1
Stage V sporulation protein AE.
 
  
 0.965
SFG17847.1
Stage V sporulation protein AC.
 
  
 0.913
gpr
Spore protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
  
 0.912
sigF_1
RNA polymerase, sigma subunit, RpoX/SigF; Belongs to the sigma-70 factor family.
 
     0.876
spoIIAB
Stage II sporulation protein AB (anti-sigma F factor); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
   
 0.873
SFG17776.1
Stage V sporulation protein AE.
 
  
 0.850
spo0A
Two-component system, response regulator, stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.827
spoVT
Transcriptional regulator, AbrB family.
  
   
 0.800
SFG28661.1
Stage II sporulation protein P.
  
   
 0.790
Your Current Organism:
Clostridium homopropionicum
NCBI taxonomy Id: 36844
Other names: ATCC 51426, C. homopropionicum, DSM 5847, strain LuHBu1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.