STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFG39462.1Hypothetical protein. (516 aa)    
Predicted Functional Partners:
SFG39427.1
Hypothetical protein.
 
   
 0.950
hsdR_1
Type I restriction enzyme, R subunit.
  
 
 0.907
hsdS
Type I restriction enzyme, S subunit.
  
 
 0.903
SFG92800.1
Type I restriction modification DNA specificity domain-containing protein.
  
 
 0.903
hsdR_2
Type I restriction enzyme, R subunit.
  
 
 0.684
uvrB_1
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.630
SFG98772.1
Hypothetical protein.
 
    0.584
SFF98604.1
Flagellar protein FlaG.
    
   0.571
SFG45635.1
Hypothetical protein.
  
  
 0.521
SFG16342.1
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains.
  
  
 0.479
Your Current Organism:
Clostridium homopropionicum
NCBI taxonomy Id: 36844
Other names: ATCC 51426, C. homopropionicum, DSM 5847, strain LuHBu1
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