STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folPDihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (272 aa)    
Predicted Functional Partners:
sulD
Dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 0.999
fgs
Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
 
 0.996
folE_1
GTP cyclohydrolase I.
 
 
 0.961
folE_2
GTP cyclohydrolase I.
 
 
 0.961
ilvE_5
4-amino-4-deoxychorismate lyase.
 
 
 0.950
rny_3
HDIG domain-containing protein.
 
   
 0.879
SFF65783.1
7, 8-dihydropterin-6-yl-methyl-4-(beta-D- ribofuranosyl)aminobenzene 5'-phosphate synthase.
     
 0.860
rbn_3
7, 8-dihydropterin-6-yl-methyl-4-(beta-D- ribofuranosyl)aminobenzene 5'-phosphate synthase.
     
 0.860
pabB
Aminodeoxychorismate synthase, subunit I.
 
 
 0.788
trpE
Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]
 
 
 0.717
Your Current Organism:
Clostridium homopropionicum
NCBI taxonomy Id: 36844
Other names: ATCC 51426, C. homopropionicum, DSM 5847, strain LuHBu1
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