lsrK_1 protein (Anaerotignum neopropionicum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

lsrK_1

Autoinducer 2 kinase LsrK. (520 aa)

Predicted Functional Partners:

KXL54246.1

0.944

lsrR_1

0.880

KXL54371.1

0.800

lsrB_1

0.791

lsrB_2

0.791

rpe

0.781

lsrR_2

0.743

lsrF_1

0.701

lsrF_2

0.701

KXL52927.1

0.564

Your Current Organism:

Anaerotignum neopropionicum

NCBI taxonomy Id: 36847
Other names: A. neopropionicum, Clostridium neopropionicum, DSM 3847, KCTC 15564, strain X4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KXL52927.1	lsrK_1	CLNEO_14690	CLNEO_03490	Hypothetical protein.	Autoinducer 2 kinase LsrK.	0.564
KXL54246.1	lsrB_1	CLNEO_03480	CLNEO_03540	Hypothetical protein.	Autoinducer 2-binding protein LsrB precursor.	0.771
KXL54246.1	lsrB_2	CLNEO_03480	CLNEO_04830	Hypothetical protein.	Autoinducer 2-binding protein LsrB precursor.	0.771
KXL54246.1	lsrF_1	CLNEO_03480	CLNEO_03550	Hypothetical protein.	Putative aldolase LsrF.	0.719
KXL54246.1	lsrF_2	CLNEO_03480	CLNEO_04840	Hypothetical protein.	Putative aldolase LsrF.	0.719
KXL54246.1	lsrK_1	CLNEO_03480	CLNEO_03490	Hypothetical protein.	Autoinducer 2 kinase LsrK.	0.944
KXL54246.1	lsrR_1	CLNEO_03480	CLNEO_03500	Hypothetical protein.	Transcriptional regulator LsrR.	0.866
KXL54246.1	lsrR_2	CLNEO_03480	CLNEO_04790	Hypothetical protein.	Transcriptional regulator LsrR.	0.731
KXL54371.1	lsrB_1	CLNEO_04770	CLNEO_03540	Hypothetical protein.	Autoinducer 2-binding protein LsrB precursor.	0.771
KXL54371.1	lsrB_2	CLNEO_04770	CLNEO_04830	Hypothetical protein.	Autoinducer 2-binding protein LsrB precursor.	0.771
KXL54371.1	lsrF_1	CLNEO_04770	CLNEO_03550	Hypothetical protein.	Putative aldolase LsrF.	0.719
KXL54371.1	lsrF_2	CLNEO_04770	CLNEO_04840	Hypothetical protein.	Putative aldolase LsrF.	0.719
KXL54371.1	lsrK_1	CLNEO_04770	CLNEO_03490	Hypothetical protein.	Autoinducer 2 kinase LsrK.	0.800
KXL54371.1	lsrR_1	CLNEO_04770	CLNEO_03500	Hypothetical protein.	Transcriptional regulator LsrR.	0.731
KXL54371.1	lsrR_2	CLNEO_04770	CLNEO_04790	Hypothetical protein.	Transcriptional regulator LsrR.	0.866
lsrB_1	KXL54246.1	CLNEO_03540	CLNEO_03480	Autoinducer 2-binding protein LsrB precursor.	Hypothetical protein.	0.771
lsrB_1	KXL54371.1	CLNEO_03540	CLNEO_04770	Autoinducer 2-binding protein LsrB precursor.	Hypothetical protein.	0.771
lsrB_1	lsrF_1	CLNEO_03540	CLNEO_03550	Autoinducer 2-binding protein LsrB precursor.	Putative aldolase LsrF.	0.811
lsrB_1	lsrF_2	CLNEO_03540	CLNEO_04840	Autoinducer 2-binding protein LsrB precursor.	Putative aldolase LsrF.	0.668
lsrB_1	lsrK_1	CLNEO_03540	CLNEO_03490	Autoinducer 2-binding protein LsrB precursor.	Autoinducer 2 kinase LsrK.	0.791

page 1 of 4

Network Stats

number of nodes:

3

number of edges:

2

average node degree:

1.33

avg. local clustering coefficient:

0.667

expected number of edges:

2

PPI enrichment p-value:

0.526

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7656

Sugar/inositol transporter, and Copper amine oxidase

3 of 30

2.52

3.42

5.21e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04113

Meiosis - yeast

3 of 157

1.8

2.09

0.00063

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-429593

Inositol transporters

3 of 70

2.15

2.57

0.00037

MAP-425366

Transport of bile salts and organic acids, metal ions and amine compounds

3 of 118

1.92

2.15

0.00086

MAP-425407

SLC-mediated transmembrane transport

3 of 236

1.62

1.5

0.0045

MAP-382551

Transport of small molecules

3 of 413

1.38

1.03

0.0177

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF07690

Major Facilitator Superfamily

3 of 199

1.69

1.43

0.0079

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR005829

Sugar transporter, conserved site

3 of 55

2.25

2.55

0.00052

IPR005828

Major facilitator, sugar transporter-like

3 of 64

2.19

2.5

0.00052

IPR020846

Major facilitator superfamily domain

3 of 190

1.71

1.49

0.0066

IPR036259

MFS transporter superfamily

3 of 272

1.56

1.2

0.0144

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