STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (170 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 0.988
purH
Bifunctional purine biosynthesis protein PurH.
  
 0.945
guaB
Inosine-5'-monophosphate dehydrogenase.
  
 
 0.929
deoD
Purine nucleoside phosphorylase DeoD-type.
    
 0.908
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
     
 0.903
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.900
purB
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.898
hpt
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
   
 0.868
add2
Aminodeoxyfutalosine deaminase.
   
 0.844
recJ
single-stranded-DNA-specific exonuclease RecJ.
  
    0.842
Your Current Organism:
Anaerotignum neopropionicum
NCBI taxonomy Id: 36847
Other names: A. neopropionicum, Clostridium neopropionicum, DSM 3847, KCTC 15564, strain X4
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