STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (300 aa)    
Predicted Functional Partners:
thrC
Threonine synthase.
 
 0.999
hom
Homoserine dehydrogenase.
 
 0.997
lysC
Aspartokinase; Belongs to the aspartokinase family.
  
 0.934
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
 
    
 0.907
yclM
Aspartokinase 3.
 
 0.800
cysE
Serine acetyltransferase.
     
 0.794
luxS
S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
  
  0.785
sdhB
L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.779
mdeA_2
Methionine gamma-lyase.
  
 
 0.779
mdeA_1
Methionine gamma-lyase.
    
  0.765
Your Current Organism:
Anaerotignum neopropionicum
NCBI taxonomy Id: 36847
Other names: A. neopropionicum, Clostridium neopropionicum, DSM 3847, KCTC 15564, strain X4
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