STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yitJ_2Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase. (521 aa)    
Predicted Functional Partners:
gcvT
Aminomethyltransferase.
  
 
 0.956
KPU43811.1
Carbon monoxide dehydrogenase/acetyl-CoA synthase subunit alpha.
 
  
 0.908
KPU44252.1
Carbon monoxide dehydrogenase/acetyl-CoA synthase subunit alpha.
 
  
 0.906
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.894
yitJ_4
Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.
  
 
 0.892
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
    
 0.877
mccB
Cystathionine gamma-lyase.
  
 0.873
mdeA_2
Methionine gamma-lyase.
  
 0.873
acsC
Corrinoid/iron-sulfur protein large subunit.
 
  
 0.866
nifJ_2
Pyruvate-flavodoxin oxidoreductase.
    
 0.864
Your Current Organism:
Oxobacter pfennigii
NCBI taxonomy Id: 36849
Other names: ATCC 43583, Clostridium pfennigii, DSM 3222, O. pfennigii, strain V5-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.