STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tipA_1HTH-type transcriptional activator TipA. (269 aa)    
Predicted Functional Partners:
gltB_2
Ferredoxin-dependent glutamate synthase 1.
    
 0.788
urdA_1
Urocanate reductase precursor.
 
     0.729
bmrR_1
Multidrug-efflux transporter 1 regulator.
  
     0.663
phoR_7
Alkaline phosphatase synthesis sensor protein PhoR.
  
 
   0.631
zraS
Sensor protein ZraS.
   
 0.624
hmrR_1
HTH-type transcriptional regulator HmrR.
  
   
 0.583
gmr_4
Cyclic di-GMP phosphodiesterase Gmr.
    
 0.572
pknB
Serine/threonine-protein kinase PknB.
  
 0.566
comC_1
Type 4 prepilin-like proteins leader peptide-processing enzyme.
   
   0.561
dnaJ_1
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.541
Your Current Organism:
Oxobacter pfennigii
NCBI taxonomy Id: 36849
Other names: ATCC 43583, Clostridium pfennigii, DSM 3222, O. pfennigii, strain V5-2
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