STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trxA_2Thioredoxin. (106 aa)    
Predicted Functional Partners:
trxB_2
Thioredoxin reductase.
 
 0.986
trxB_1
Thioredoxin reductase.
 
 0.967
grdA
Glycine/sarcosine/betaine reductase complex component A; In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination.
 
   
 0.922
grdC
Glycine/sarcosine/betaine reductase complex component C subunit beta.
 
   
 0.880
grdD
Glycine/sarcosine/betaine reductase complex component C subunit alpha.
 
     0.868
arsC1
Arsenate-mycothiol transferase ArsC1; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.867
thrS
threonine--tRNA ligase 1.
   
 
 0.862
gltB_2
Ferredoxin-dependent glutamate synthase 1.
   
 
 0.834
preA
NAD-dependent dihydropyrimidine dehydrogenase subunit PreA.
  
 0.827
ribBA
Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.809
Your Current Organism:
Oxobacter pfennigii
NCBI taxonomy Id: 36849
Other names: ATCC 43583, Clostridium pfennigii, DSM 3222, O. pfennigii, strain V5-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.