STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
cobQ_2Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (483 aa)    
Predicted Functional Partners:
cobU
Bifunctional adenosylcobalamin biosynthesis protein CobU.
 
 0.986
cbiH
cobalt-precorrin-3B C(17)-methyltransferase.
  
 0.978
cobD
Threonine-phosphate decarboxylase.
 
 0.962
cbiB
Cobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 0.949
cbiC
cobalt-precorrin-8X methylmutase.
  
 0.928
cobB
Cobyrinic acid A,C-diamide synthase.
  
 0.922
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.911
cbiL
Cobalt-precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.898
cobK
precorrin-6A reductase.
 
  
 0.890
cbiT
Putative cobalt-precorrin-6Y C(15)-methyltransferase.
 
  
 0.889
Your Current Organism:
Oxobacter pfennigii
NCBI taxonomy Id: 36849
Other names: ATCC 43583, Clostridium pfennigii, DSM 3222, O. pfennigii, strain V5-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.