STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPU42665.1UvrB/uvrC motif protein. (169 aa)    
Predicted Functional Partners:
mcsB
Putative ATP:guanido phosphotransferase; Catalyzes the specific phosphorylation of arginine residues in proteins.
 
  
 0.997
ctsR
Transcriptional regulator CtsR; Belongs to the CtsR family.
 
  
 0.989
clpC_2
Negative regulator of genetic competence ClpC/MecB; Belongs to the ClpA/ClpB family.
 
  
 0.977
clpC_1
ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family.
 
  
 0.807
radA
Hypothetical protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
    0.798
disA_2
DNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
  
  
 0.727
ywlE
Low molecular weight protein-tyrosine-phosphatase YwlE.
  
   
 0.683
KPU42658.1
Putative PIN and TRAM-domain containing protein precursor.
  
    0.489
rpfG_6
Cyclic di-GMP phosphodiesterase response regulator RpfG.
       0.409
fusA_2
Elongation factor G.
       0.402
Your Current Organism:
Oxobacter pfennigii
NCBI taxonomy Id: 36849
Other names: ATCC 43583, Clostridium pfennigii, DSM 3222, O. pfennigii, strain V5-2
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.