STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobBCobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (431 aa)    
Predicted Functional Partners:
OAP45883.1
Adenosylcobinamide kinase/adenosylcobinamide phosphate guanyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
 
 
 0.985
cobD
Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 
 0.983
cobH
Catalyzes the interconversion of precorrin-8X and hydrogenobyrinate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.982
OAP35786.1
Catalyzes the formation of precorrin-4 from precorrin-3B and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.967
cobQ
Cobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.966
OAP45878.1
Cobalamin biosynthesis protein CobE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.964
OAP45881.1
Cobalt chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.958
OAP45875.1
Threonine-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.944
OAP45880.1
cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
 
 
 0.931
OAP35783.1
Precorrin-4 C11-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.
 
 
 0.921
Your Current Organism:
Sinorhizobium saheli
NCBI taxonomy Id: 36856
Other names: ATCC 51690, DSM 11273, Ensifer saheli, HAMBI 215, ICMP 13648, LMG 7837, LMG:7837, NBRC 100386, ORS 609, S. saheli, Sinorhizobium sp. HAMBI1496
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.