node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AYY16_07000 | OBU08488.1 | AYY16_07000 | AYY16_04060 | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.987 |
AYY16_07000 | clpP | AYY16_07000 | AYY16_15795 | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.577 |
AYY16_07000 | dnaK | AYY16_07000 | AYY16_15150 | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaJ; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.987 |
AYY16_07000 | groES | AYY16_07000 | AYY16_09895 | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Co-chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.827 |
AYY16_07000 | groL | AYY16_07000 | AYY16_09900 | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.901 |
AYY16_07000 | grpE | AYY16_07000 | AYY16_07120 | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.987 |
AYY16_07000 | hscA | AYY16_07000 | AYY16_01830 | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. | 0.987 |
AYY16_07000 | hslU | AYY16_07000 | AYY16_14625 | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | HslU--HslV peptidase ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.811 |
AYY16_07000 | htpG | AYY16_07000 | AYY16_15645 | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. | 0.994 |
OBU08488.1 | AYY16_07000 | AYY16_04060 | AYY16_07000 | Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.987 |
OBU08488.1 | clpP | AYY16_04060 | AYY16_15795 | Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.604 |
OBU08488.1 | groES | AYY16_04060 | AYY16_09895 | Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. | Co-chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.836 |
OBU08488.1 | groL | AYY16_04060 | AYY16_09900 | Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.921 |
OBU08488.1 | grpE | AYY16_04060 | AYY16_07120 | Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.971 |
OBU08488.1 | hslU | AYY16_04060 | AYY16_14625 | Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. | HslU--HslV peptidase ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.557 |
OBU08488.1 | htpG | AYY16_04060 | AYY16_15645 | Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. | 0.986 |
clpP | AYY16_07000 | AYY16_15795 | AYY16_07000 | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.577 |
clpP | OBU08488.1 | AYY16_15795 | AYY16_04060 | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.604 |
clpP | dnaK | AYY16_15795 | AYY16_15150 | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Molecular chaperone DnaJ; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.611 |
clpP | groES | AYY16_15795 | AYY16_09895 | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Co-chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.844 |