STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A2K1Y735DNA_MISMATCH_REPAIR_2 domain-containing protein. (695 aa)    
Predicted Functional Partners:
A0A2K2AEN2
Uncharacterized protein.
 
  
 0.548
A0A2K1WRA7
DNA_mis_repair domain-containing protein.
 
  
 0.529
B9IMJ0_POPTR
Uncharacterized protein.
    
   0.513
B9I9S8_POPTR
Uncharacterized protein.
 
  
 0.508
A0A3N7FKD3
DNA_MISMATCH_REPAIR_2 domain-containing protein.
 
  
 0.507
B9HVB4_POPTR
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
  
  
 0.486
B9GJU7_POPTR
Uncharacterized protein.
   
 
 0.481
U7E2I6_POPTR
Uncharacterized protein.
   
 
 0.481
NTH1
Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
     
 0.445
A0A2K2BCS3
50S ribosomal protein L31; Belongs to the bacterial ribosomal protein bL31 family.
    
   0.442
Your Current Organism:
Populus trichocarpa
NCBI taxonomy Id: 3694
Other names: P. trichocarpa, Populus balsamifera subsp. trichocarpa, Populus balsamifera subsp. trichocarpa (Torr. & A.Gray) Brayshaw, Populus trichocarpa Torr. & A.Gray, black cottonwood, western balsam poplar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.