STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B9HK13_POPTRSerine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (520 aa)    
Predicted Functional Partners:
A0A2K1Z2V3
Aminotran_5 domain-containing protein.
  
 0.980
B9GIG2_POPTR
Aminotran_5 domain-containing protein.
  
 0.980
A0A2K2AN88
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
  
 0.979
U7E312_POPTR
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
  
 0.979
B9GLK3_POPTR
Uncharacterized protein.
  
 0.978
B9GYJ7_POPTR
Uncharacterized protein.
  
 0.978
A0A2K2AL36
DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.
  
 
 0.976
A0A2K2AVA6
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
  
 
 0.976
A0A3N7GB50
DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.
  
 
 0.976
B9HRK6_POPTR
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
  
 
 0.976
Your Current Organism:
Populus trichocarpa
NCBI taxonomy Id: 3694
Other names: P. trichocarpa, Populus balsamifera subsp. trichocarpa, Populus balsamifera subsp. trichocarpa (Torr. & A.Gray) Brayshaw, Populus trichocarpa Torr. & A.Gray, black cottonwood, western balsam poplar
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