STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFZ93854.1Molecular chaperone HtpG. (637 aa)    
Predicted Functional Partners:
SFZ92896.1
FKBP-type peptidyl-prolyl cis-trans isomerase.
   
 0.999
SFZ93285.1
Peptidylprolyl isomerase.
   
 0.999
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.999
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.941
SFZ89927.1
DnaJ like chaperone protein.
  
 0.929
SFZ91609.1
DnaJ domain-containing protein.
  
 0.924
SFZ92305.1
Curved DNA-binding protein.
  
 0.924
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 0.924
SFZ90468.1
Sulfite reductase (NADPH) flavoprotein alpha-component.
    
 0.912
SFZ93909.1
Peptidyl-prolyl cis-trans isomerase (rotamase)-cyclophilin family; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.874
Your Current Organism:
Flaviramulus basaltis
NCBI taxonomy Id: 369401
Other names: CIP 109091, DSM 18180, F. basaltis, Flaviramulus basaltis Einen and Ovreas 2006 emend. Zhang et al. 2013, strain H35
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.