Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABP53423.1FO synthase subunit 2 / FO synthase subunit 1; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (860 aa)    
Predicted Functional Partners:
ABP53421.1
LPPG:FO 2-phospho-L-lactate transferase; TIGRFAM: LPPG domain containing protein; PFAM: protein of unknown function UPF0052 and CofD.
 
  
 0.991
ABP53420.1
TIGRFAM: F420-dependent oxidoreductase, putative; PFAM: protein of unknown function DUF129.
 
   
 0.903
ABP56534.1
Stage II sporulation E family protein; PFAM: GAF domain protein; ATP-binding region, ATPase domain protein domain protein; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein.
   
    0.885
thiG
Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 
 0.825
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.796
fbiD
Hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
 
   
 0.791
ABP56317.1
TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein.
  
  
 0.762
ABP56315.1
PFAM: thiamine monophosphate synthase.
  
  
 0.746
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.746
ABP53618.1
Coenzyme F420-0 gamma-glutamyl ligase; PFAM: protein of unknown function DUF129.
 
   
 0.743
Your Current Organism:
Salinispora tropica
NCBI taxonomy Id: 369723
Other names: S. tropica CNB-440, Salinispora sp. CNB-440, Salinispora tropica ATCC BAA-916, Salinispora tropica CNB-440, Salinispora tropica str. CNB-440, Salinispora tropica strain CNB-440
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