Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABP53501.1PFAM: short-chain dehydrogenase/reductase SDR; KR. (255 aa)    
Predicted Functional Partners:
ABP55121.1
PFAM: MaoC domain protein dehydratase.
 
 
 0.924
ABP56611.1
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR.
  
 
 
 0.746
ABP54641.1
PFAM: short-chain dehydrogenase/reductase SDR; KR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
     0.695
ABP56845.1
TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.675
ABP55273.1
PFAM: condensation domain protein.
  
 
 0.598
ABP53327.1
PFAM: O-methyltransferase, family 3.
 
  
   0.582
ABP53503.1
PFAM: cyclase family protein.
 
  
 0.556
ABP55408.1
PFAM: short-chain dehydrogenase/reductase SDR.
  
 
   0.488
salL
Protein of unknown function DUF62; Involved in the biosynthesis of the proteosome inhibitor salinosporamide A (SalA). Catalyzes the halogenation of S-adenosyl-L- methionine (SAM) with chloride to generate 5'-chloro-5'-deoxyadenosine (5'-CIDA) and L-methionine. It can also use bromide and iodide, producing halogenated 5'-deoxyadenosine (5'-XDA) and L-methionine, however no halogenase activity is detected in the presence of fluoride.
       0.486
ABP55493.1
TIGRFAM: thioester reductase domain; PFAM: GCN5-related N-acetyltransferase; beta-ketoacyl synthase; AMP-dependent synthetase and ligase; acyl transferase domain protein; NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; phosphopantetheine-binding; Male sterility C-terminal domain.
  
 
 0.478
Your Current Organism:
Salinispora tropica
NCBI taxonomy Id: 369723
Other names: S. tropica CNB-440, Salinispora sp. CNB-440, Salinispora tropica ATCC BAA-916, Salinispora tropica CNB-440, Salinispora tropica str. CNB-440, Salinispora tropica strain CNB-440
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