ABP55444.1 protein (Salinispora tropica) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

ABP55444.1

Transcriptional regulator, CdaR family; PFAM: purine catabolism PurC domain protein. (596 aa)

Predicted Functional Partners:

ABP55445.1

0.574

ABP55793.1

0.562

ABP55023.1

0.500

ABP54269.1

0.494

ABP54648.1

0.447

ABP56393.1

0.443

ABP55245.1

0.429

ABP55446.1

0.427

ABP56139.1

0.410

ABP55203.1

0.408

Your Current Organism:

Salinispora tropica

NCBI taxonomy Id: 369723
Other names: S. tropica CNB-440, Salinispora sp. CNB-440, Salinispora tropica ATCC BAA-916, Salinispora tropica CNB-440, Salinispora tropica str. CNB-440, Salinispora tropica strain CNB-440

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABP54269.1	ABP55444.1	Strop_1806	Strop_3007	PFAM: GAF domain protein.	Transcriptional regulator, CdaR family; PFAM: purine catabolism PurC domain protein.	0.494
ABP54648.1	ABP55444.1	Strop_2197	Strop_3007	PFAM: cyclase/dehydrase.	Transcriptional regulator, CdaR family; PFAM: purine catabolism PurC domain protein.	0.447
ABP55023.1	ABP55444.1	Strop_2579	Strop_3007	Hypothetical protein.	Transcriptional regulator, CdaR family; PFAM: purine catabolism PurC domain protein.	0.500
ABP55023.1	ABP55793.1	Strop_2579	Strop_3360	Hypothetical protein.	Hypothetical protein.	0.643
ABP55203.1	ABP55444.1	Strop_2761	Strop_3007	PFAM: regulatory protein, LuxR.	Transcriptional regulator, CdaR family; PFAM: purine catabolism PurC domain protein.	0.408
ABP55245.1	ABP55444.1	Strop_2804	Strop_3007	PFAM: FAD dependent oxidoreductase.	Transcriptional regulator, CdaR family; PFAM: purine catabolism PurC domain protein.	0.429
ABP55444.1	ABP54269.1	Strop_3007	Strop_1806	Transcriptional regulator, CdaR family; PFAM: purine catabolism PurC domain protein.	PFAM: GAF domain protein.	0.494
ABP55444.1	ABP54648.1	Strop_3007	Strop_2197	Transcriptional regulator, CdaR family; PFAM: purine catabolism PurC domain protein.	PFAM: cyclase/dehydrase.	0.447
ABP55444.1	ABP55023.1	Strop_3007	Strop_2579	Transcriptional regulator, CdaR family; PFAM: purine catabolism PurC domain protein.	Hypothetical protein.	0.500
ABP55444.1	ABP55203.1	Strop_3007	Strop_2761	Transcriptional regulator, CdaR family; PFAM: purine catabolism PurC domain protein.	PFAM: regulatory protein, LuxR.	0.408
ABP55444.1	ABP55245.1	Strop_3007	Strop_2804	Transcriptional regulator, CdaR family; PFAM: purine catabolism PurC domain protein.	PFAM: FAD dependent oxidoreductase.	0.429
ABP55444.1	ABP55445.1	Strop_3007	Strop_3008	Transcriptional regulator, CdaR family; PFAM: purine catabolism PurC domain protein.	PFAM: tRNA/rRNA methyltransferase (SpoU).	0.574
ABP55444.1	ABP55446.1	Strop_3007	Strop_3009	Transcriptional regulator, CdaR family; PFAM: purine catabolism PurC domain protein.	PFAM: protein of unknown function DUF397.	0.427
ABP55444.1	ABP55793.1	Strop_3007	Strop_3360	Transcriptional regulator, CdaR family; PFAM: purine catabolism PurC domain protein.	Hypothetical protein.	0.562
ABP55444.1	ABP56139.1	Strop_3007	Strop_3708	Transcriptional regulator, CdaR family; PFAM: purine catabolism PurC domain protein.	PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein.	0.410
ABP55444.1	ABP56393.1	Strop_3007	Strop_3963	Transcriptional regulator, CdaR family; PFAM: purine catabolism PurC domain protein.	Hypothetical protein.	0.443
ABP55445.1	ABP55444.1	Strop_3008	Strop_3007	PFAM: tRNA/rRNA methyltransferase (SpoU).	Transcriptional regulator, CdaR family; PFAM: purine catabolism PurC domain protein.	0.574
ABP55445.1	ABP55446.1	Strop_3008	Strop_3009	PFAM: tRNA/rRNA methyltransferase (SpoU).	PFAM: protein of unknown function DUF397.	0.681
ABP55446.1	ABP55444.1	Strop_3009	Strop_3007	PFAM: protein of unknown function DUF397.	Transcriptional regulator, CdaR family; PFAM: purine catabolism PurC domain protein.	0.427
ABP55446.1	ABP55445.1	Strop_3009	Strop_3008	PFAM: protein of unknown function DUF397.	PFAM: tRNA/rRNA methyltransferase (SpoU).	0.681

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Network Stats

number of nodes:

11

number of edges:

27

average node degree:

4.91

avg. local clustering coefficient:

0.913

expected number of edges:

26

PPI enrichment p-value:

0.464

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 272

1.7

4.24

8.45e-16

GO:0032543

Mitochondrial translation

5 of 43

2.16

3.53

4.14e-08

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

11 of 152

1.95

6.09

7.34e-19

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005761

Mitochondrial ribosome

11 of 61

2.35

9.44

3.08e-23

GO:0005762

Mitochondrial large ribosomal subunit

9 of 33

2.53

8.95

1.05e-19

GO:0044391

Ribosomal subunit

11 of 140

1.99

6.52

5.46e-20

GO:0098798

Mitochondrial protein-containing complex

11 of 173

1.9

5.86

2.20e-19

GO:0005763

Mitochondrial small ribosomal subunit

2 of 24

2.01

1.14

0.0064

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6472

Organellar ribosome

11 of 64

2.33

9.15

1.14e-22

CL:6476

Organellar ribosome

6 of 22

2.53

5.66

5.68e-12

CL:6546

Organellar large ribosomal subunit, and Ribosomal protein S9

5 of 21

2.47

4.46

1.69e-09

CL:6504

Mixed, incl. Ribosomal protein L25/L23, and Ribosomal protein L30p/L7e

2 of 5

2.7

1.48

0.0020

CL:6549

Mixed, incl. Ribosomal protein S9, and Ribosomal protein L25/L23

2 of 6

2.62

1.43

0.0024

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

7 of 177

1.69

3.02

3.43e-09

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72766

Translation

11 of 259

1.72

4.45

1.38e-16

MAP-392499

Metabolism of proteins

11 of 969

1.15

1.67

1.15e-10

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005762

Mitochondrial large ribosomal subunit

9 of 32

2.54

9.03

8.28e-20

GOCC:0005761

Mitochondrial ribosome

11 of 69

2.3

8.96

1.34e-22

GOCC:0044391

Ribosomal subunit

11 of 146

1.97

6.38

7.99e-20

GOCC:0098798

Mitochondrial protein complex

11 of 160

1.93

6.12

1.05e-19

GOCC:0005763

Mitochondrial small ribosomal subunit

2 of 36

1.84

0.92

0.0165

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

6 of 106

1.85

3.12

2.79e-08

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