node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSKMAP00000013340 | ciapin1 | ENSKMAP00000013340 | ENSKMAP00000021745 | Uncharacterized protein. | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] | 0.404 |
ENSKMAP00000013340 | narf | ENSKMAP00000013340 | ENSKMAP00000002641 | Uncharacterized protein. | Nuclear prelamin A recognition factor; Belongs to the NARF family. | 0.713 |
ciao1 | ciao2a | ENSKMAP00000005033 | ENSKMAP00000012963 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. | Cytosolic iron-sulfur assembly component 2A. | 0.973 |
ciao1 | ciao2b | ENSKMAP00000005033 | ENSKMAP00000021438 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. | Cytosolic iron-sulfur assembly component 2B. | 0.998 |
ciao1 | ciapin1 | ENSKMAP00000005033 | ENSKMAP00000021745 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] | 0.663 |
ciao1 | mms19 | ENSKMAP00000005033 | ENSKMAP00000002221 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. | MMS19 homolog, cytosolic iron-sulfur assembly component. | 0.989 |
ciao1 | narf | ENSKMAP00000005033 | ENSKMAP00000002641 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. | Nuclear prelamin A recognition factor; Belongs to the NARF family. | 0.841 |
ciao1 | nubp1 | ENSKMAP00000005033 | ENSKMAP00000024423 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.669 |
ciao1 | nubp2 | ENSKMAP00000005033 | ENSKMAP00000018435 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. | Cytosolic Fe-S cluster assembly factor NUBP2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. | 0.681 |
ciao1 | nubpl | ENSKMAP00000005033 | ENSKMAP00000013566 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. | Nucleotide binding protein-like. | 0.533 |
ciao2a | ciao1 | ENSKMAP00000012963 | ENSKMAP00000005033 | Cytosolic iron-sulfur assembly component 2A. | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. | 0.973 |
ciao2a | ciapin1 | ENSKMAP00000012963 | ENSKMAP00000021745 | Cytosolic iron-sulfur assembly component 2A. | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] | 0.564 |
ciao2a | mms19 | ENSKMAP00000012963 | ENSKMAP00000002221 | Cytosolic iron-sulfur assembly component 2A. | MMS19 homolog, cytosolic iron-sulfur assembly component. | 0.970 |
ciao2a | narf | ENSKMAP00000012963 | ENSKMAP00000002641 | Cytosolic iron-sulfur assembly component 2A. | Nuclear prelamin A recognition factor; Belongs to the NARF family. | 0.768 |
ciao2a | nubp1 | ENSKMAP00000012963 | ENSKMAP00000024423 | Cytosolic iron-sulfur assembly component 2A. | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.417 |
ciao2a | nubp2 | ENSKMAP00000012963 | ENSKMAP00000018435 | Cytosolic iron-sulfur assembly component 2A. | Cytosolic Fe-S cluster assembly factor NUBP2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. | 0.417 |
ciao2a | nubpl | ENSKMAP00000012963 | ENSKMAP00000013566 | Cytosolic iron-sulfur assembly component 2A. | Nucleotide binding protein-like. | 0.417 |
ciao2b | ciao1 | ENSKMAP00000021438 | ENSKMAP00000005033 | Cytosolic iron-sulfur assembly component 2B. | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. | 0.998 |
ciao2b | ciapin1 | ENSKMAP00000021438 | ENSKMAP00000021745 | Cytosolic iron-sulfur assembly component 2B. | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] | 0.662 |
ciao2b | mms19 | ENSKMAP00000021438 | ENSKMAP00000002221 | Cytosolic iron-sulfur assembly component 2B. | MMS19 homolog, cytosolic iron-sulfur assembly component. | 0.990 |