node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC108242506 | acadm | ENSKMAP00000021391 | ENSKMAP00000024967 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acyl-CoA dehydrogenase medium chain. | 0.420 |
LOC108242506 | acat1 | ENSKMAP00000021391 | ENSKMAP00000002715 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 0.994 |
LOC108242506 | cs | ENSKMAP00000021391 | ENSKMAP00000007609 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Citrate synthase; Belongs to the citrate synthase family. | 0.861 |
LOC108242506 | eci2 | ENSKMAP00000021391 | ENSKMAP00000002607 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Enoyl-CoA delta isomerase 2. | 0.620 |
LOC108242506 | ehhadh | ENSKMAP00000021391 | ENSKMAP00000016212 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.957 |
LOC108242506 | hadh | ENSKMAP00000021391 | ENSKMAP00000002449 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Hydroxyacyl-CoA dehydrogenase. | 0.920 |
LOC108242506 | hadha | ENSKMAP00000021391 | ENSKMAP00000018226 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.592 |
LOC108242506 | oxct1 | ENSKMAP00000021391 | ENSKMAP00000018057 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.961 |
acadm | LOC108242506 | ENSKMAP00000024967 | ENSKMAP00000021391 | Acyl-CoA dehydrogenase medium chain. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.420 |
acadm | acat1 | ENSKMAP00000024967 | ENSKMAP00000002715 | Acyl-CoA dehydrogenase medium chain. | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 0.958 |
acadm | acox1 | ENSKMAP00000024967 | ENSKMAP00000015462 | Acyl-CoA dehydrogenase medium chain. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.960 |
acadm | acox3 | ENSKMAP00000024967 | ENSKMAP00000010325 | Acyl-CoA dehydrogenase medium chain. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.954 |
acadm | cs | ENSKMAP00000024967 | ENSKMAP00000007609 | Acyl-CoA dehydrogenase medium chain. | Citrate synthase; Belongs to the citrate synthase family. | 0.417 |
acadm | eci2 | ENSKMAP00000024967 | ENSKMAP00000002607 | Acyl-CoA dehydrogenase medium chain. | Enoyl-CoA delta isomerase 2. | 0.896 |
acadm | ehhadh | ENSKMAP00000024967 | ENSKMAP00000016212 | Acyl-CoA dehydrogenase medium chain. | Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.971 |
acadm | hadh | ENSKMAP00000024967 | ENSKMAP00000002449 | Acyl-CoA dehydrogenase medium chain. | Hydroxyacyl-CoA dehydrogenase. | 0.882 |
acadm | hadha | ENSKMAP00000024967 | ENSKMAP00000018226 | Acyl-CoA dehydrogenase medium chain. | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.980 |
acadm | oxct1 | ENSKMAP00000024967 | ENSKMAP00000018057 | Acyl-CoA dehydrogenase medium chain. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.578 |
acat1 | LOC108242506 | ENSKMAP00000002715 | ENSKMAP00000021391 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.994 |
acat1 | acadm | ENSKMAP00000002715 | ENSKMAP00000024967 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Acyl-CoA dehydrogenase medium chain. | 0.958 |