STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbrg1Transforming growth factor beta regulator 1. (546 aa)    
Predicted Functional Partners:
rbbp5
Retinoblastoma binding protein 5.
    
 0.785
ash2l
Ash2 like, histone lysine methyltransferase complex subunit.
    
 0.779
cops2
COP9 signalosome subunit 2.
   
  
 0.667
tsku
Tsukushi small leucine rich proteoglycan homolog (Xenopus laevis).
      
 0.662
P2RY6
Pyrimidinergic receptor P2Y6.
      
 0.662
p2ry2
Purinergic receptor P2Y2, tandem duplicate 1; Belongs to the G-protein coupled receptor 1 family.
      
 0.662
cenpn
Centromere protein N.
   
 0.652
LOC108240031
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.639
LOC108247233
Histone H4.
    
 0.639
LOC108229777
Histone H4.
    
 0.639
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.