node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC108240031 | ash2l | ENSKMAP00000009485 | ENSKMAP00000022617 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Ash2 like, histone lysine methyltransferase complex subunit. | 0.880 |
LOC108240031 | eed | ENSKMAP00000009485 | ENSKMAP00000004096 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Embryonic ectoderm development. | 0.695 |
LOC108240031 | mre11 | ENSKMAP00000009485 | ENSKMAP00000012071 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.717 |
LOC108240031 | nsd3 | ENSKMAP00000009485 | ENSKMAP00000004142 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Nuclear receptor binding SET domain protein 3. | 0.580 |
LOC108240031 | rbbp5 | ENSKMAP00000009485 | ENSKMAP00000016437 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Retinoblastoma binding protein 5. | 0.891 |
LOC108240031 | setd7 | ENSKMAP00000009485 | ENSKMAP00000010696 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | SET domain containing 7, histone lysine methyltransferase. | 0.576 |
ash2l | LOC108240031 | ENSKMAP00000022617 | ENSKMAP00000009485 | Ash2 like, histone lysine methyltransferase complex subunit. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.880 |
ash2l | nsd3 | ENSKMAP00000022617 | ENSKMAP00000004142 | Ash2 like, histone lysine methyltransferase complex subunit. | Nuclear receptor binding SET domain protein 3. | 0.666 |
ash2l | rbbp5 | ENSKMAP00000022617 | ENSKMAP00000016437 | Ash2 like, histone lysine methyltransferase complex subunit. | Retinoblastoma binding protein 5. | 0.999 |
ash2l | setd3 | ENSKMAP00000022617 | ENSKMAP00000002563 | Ash2 like, histone lysine methyltransferase complex subunit. | Protein-histidine N-methyltransferase. | 0.548 |
ash2l | setd7 | ENSKMAP00000022617 | ENSKMAP00000010696 | Ash2 like, histone lysine methyltransferase complex subunit. | SET domain containing 7, histone lysine methyltransferase. | 0.718 |
camkmt | nsd3 | ENSKMAP00000004474 | ENSKMAP00000004142 | Calmodulin-lysine N-methyltransferase. | Nuclear receptor binding SET domain protein 3. | 0.677 |
camkmt | plod1 | ENSKMAP00000004474 | ENSKMAP00000002737 | Calmodulin-lysine N-methyltransferase. | Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a. | 0.900 |
camkmt | plod2 | ENSKMAP00000004474 | ENSKMAP00000015769 | Calmodulin-lysine N-methyltransferase. | Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2. | 0.900 |
camkmt | setd7 | ENSKMAP00000004474 | ENSKMAP00000010696 | Calmodulin-lysine N-methyltransferase. | SET domain containing 7, histone lysine methyltransferase. | 0.721 |
eed | LOC108240031 | ENSKMAP00000004096 | ENSKMAP00000009485 | Embryonic ectoderm development. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.695 |
eed | nsd3 | ENSKMAP00000004096 | ENSKMAP00000004142 | Embryonic ectoderm development. | Nuclear receptor binding SET domain protein 3. | 0.657 |
eed | setd7 | ENSKMAP00000004096 | ENSKMAP00000010696 | Embryonic ectoderm development. | SET domain containing 7, histone lysine methyltransferase. | 0.942 |
mre11 | LOC108240031 | ENSKMAP00000012071 | ENSKMAP00000009485 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.717 |
mre11 | nsd3 | ENSKMAP00000012071 | ENSKMAP00000004142 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | Nuclear receptor binding SET domain protein 3. | 0.599 |