STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSKMAP00000004211Histone domain-containing protein. (127 aa)    
Predicted Functional Partners:
LOC108242869
Lysine (K)-specific demethylase 6B, a.
   
 0.737
kdm6a
Lysine (K)-specific demethylase 6A.
   
 0.737
LOC108233868
Lysine (K)-specific demethylase 6B, b.
   
 0.737
LOC108249342
Lysine (K)-specific demethylase 6A, like.
   
 0.737
LOC108240031
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.682
LOC108247233
Histone H4.
 
 
 0.682
LOC108229777
Histone H4.
 
 
 0.682
arid4b
Translocase of outer mitochondrial membrane 20.
   
 0.629
arid4a
AT rich interactive domain 4A (RBP1-like).
   
 0.629
setd2
SET domain containing 2, histone lysine methyltransferase.
   
 0.623
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.