node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC108232686 | LOC108250956 | ENSKMAP00000016944 | ENSKMAP00000005551 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.572 |
LOC108232686 | pln | ENSKMAP00000016944 | ENSKMAP00000003222 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | 0.973 |
LOC108234992 | LOC108250956 | ENSKMAP00000009905 | ENSKMAP00000005551 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.572 |
LOC108234992 | pln | ENSKMAP00000009905 | ENSKMAP00000003222 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | 0.973 |
LOC108239664 | LOC108241350 | ENSKMAP00000020712 | ENSKMAP00000017710 | Uncharacterized protein; Belongs to the protein kinase superfamily. | Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. | 0.900 |
LOC108239664 | LOC108250956 | ENSKMAP00000020712 | ENSKMAP00000005551 | Uncharacterized protein; Belongs to the protein kinase superfamily. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.914 |
LOC108239664 | pln | ENSKMAP00000020712 | ENSKMAP00000003222 | Uncharacterized protein; Belongs to the protein kinase superfamily. | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | 0.972 |
LOC108239664 | prkaca | ENSKMAP00000020712 | ENSKMAP00000025122 | Uncharacterized protein; Belongs to the protein kinase superfamily. | Uncharacterized protein; Belongs to the protein kinase superfamily. | 0.900 |
LOC108239664 | prkacb | ENSKMAP00000020712 | ENSKMAP00000014230 | Uncharacterized protein; Belongs to the protein kinase superfamily. | Uncharacterized protein; Belongs to the protein kinase superfamily. | 0.900 |
LOC108241350 | LOC108239664 | ENSKMAP00000017710 | ENSKMAP00000020712 | Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. | Uncharacterized protein; Belongs to the protein kinase superfamily. | 0.900 |
LOC108241350 | LOC108250956 | ENSKMAP00000017710 | ENSKMAP00000005551 | Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.914 |
LOC108241350 | pln | ENSKMAP00000017710 | ENSKMAP00000003222 | Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | 0.972 |
LOC108241350 | prkaca | ENSKMAP00000017710 | ENSKMAP00000025122 | Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. | Uncharacterized protein; Belongs to the protein kinase superfamily. | 0.900 |
LOC108241350 | prkacb | ENSKMAP00000017710 | ENSKMAP00000014230 | Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. | Uncharacterized protein; Belongs to the protein kinase superfamily. | 0.900 |
LOC108246921 | LOC108250956 | ENSKMAP00000010544 | ENSKMAP00000005551 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.571 |
LOC108246921 | pln | ENSKMAP00000010544 | ENSKMAP00000003222 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | 0.968 |
LOC108250956 | LOC108232686 | ENSKMAP00000005551 | ENSKMAP00000016944 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.572 |
LOC108250956 | LOC108234992 | ENSKMAP00000005551 | ENSKMAP00000009905 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.572 |
LOC108250956 | LOC108239664 | ENSKMAP00000005551 | ENSKMAP00000020712 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Uncharacterized protein; Belongs to the protein kinase superfamily. | 0.914 |
LOC108250956 | LOC108241350 | ENSKMAP00000005551 | ENSKMAP00000017710 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. | 0.914 |