STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phf8PHD finger protein 8. (1023 aa)    
Predicted Functional Partners:
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.699
suv39h1
Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
    
 0.660
LOC108240031
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.609
LOC108247233
Histone H4.
    
 0.609
LOC108229777
Histone H4.
    
 0.609
arid5b
AT-rich interaction domain 5B.
     
 0.555
LOC108242169
Zgc:77151.
     
 0.553
setd2
SET domain containing 2, histone lysine methyltransferase.
   
 0.508
topbp1
DNA topoisomerase II binding protein 1.
    
   0.493
LOC108242801
Histone H2A; Belongs to the histone H2A family.
    
  0.483
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.