LOC108234252 protein (Kryptolebias marmoratus)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

LOC108234252

Hexosyltransferase. (420 aa)

Predicted Functional Partners:

b4galt2

0.912

LOC108251055

0.912

b4galt1

0.912

LOC108235243

0.912

LOC108250944

0.909

fut9

0.909

LOC108233304

0.909

LOC108249546

0.909

FUT4

0.909

B4galt4

0.900

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B4galt4	FUT4	ENSKMAP00000024288	ENSKMAP00000027900	Rho-GAP domain-containing protein.	Fucosyltransferase 4.	0.900
B4galt4	LOC108233304	ENSKMAP00000024288	ENSKMAP00000015697	Rho-GAP domain-containing protein.	Fucosyltransferase 9a.	0.900
B4galt4	LOC108234252	ENSKMAP00000024288	ENSKMAP00000008708	Rho-GAP domain-containing protein.	Hexosyltransferase.	0.900
B4galt4	fut9	ENSKMAP00000024288	ENSKMAP00000015676	Rho-GAP domain-containing protein.	Fucosyltransferase 9a.	0.900
FUT4	B4galt4	ENSKMAP00000027900	ENSKMAP00000024288	Fucosyltransferase 4.	Rho-GAP domain-containing protein.	0.900
FUT4	LOC108233304	ENSKMAP00000027900	ENSKMAP00000015697	Fucosyltransferase 4.	Fucosyltransferase 9a.	0.905
FUT4	LOC108234252	ENSKMAP00000027900	ENSKMAP00000008708	Fucosyltransferase 4.	Hexosyltransferase.	0.909
FUT4	LOC108235243	ENSKMAP00000027900	ENSKMAP00000026711	Fucosyltransferase 4.	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3.	0.909
FUT4	LOC108249546	ENSKMAP00000027900	ENSKMAP00000024095	Fucosyltransferase 4.	Uncharacterized protein.	0.909
FUT4	LOC108250944	ENSKMAP00000027900	ENSKMAP00000005046	Fucosyltransferase 4.	Uncharacterized protein.	0.909
FUT4	LOC108251055	ENSKMAP00000027900	ENSKMAP00000010407	Fucosyltransferase 4.	Si:dkey-199f5.8.	0.909
FUT4	b4galt1	ENSKMAP00000027900	ENSKMAP00000024682	Fucosyltransferase 4.	DP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, like.	0.909
FUT4	b4galt2	ENSKMAP00000027900	ENSKMAP00000003580	Fucosyltransferase 4.	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2.	0.909
FUT4	fut9	ENSKMAP00000027900	ENSKMAP00000015676	Fucosyltransferase 4.	Fucosyltransferase 9a.	0.903
LOC108233304	B4galt4	ENSKMAP00000015697	ENSKMAP00000024288	Fucosyltransferase 9a.	Rho-GAP domain-containing protein.	0.900
LOC108233304	FUT4	ENSKMAP00000015697	ENSKMAP00000027900	Fucosyltransferase 9a.	Fucosyltransferase 4.	0.905
LOC108233304	LOC108234252	ENSKMAP00000015697	ENSKMAP00000008708	Fucosyltransferase 9a.	Hexosyltransferase.	0.909
LOC108233304	LOC108235243	ENSKMAP00000015697	ENSKMAP00000026711	Fucosyltransferase 9a.	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3.	0.909
LOC108233304	LOC108249546	ENSKMAP00000015697	ENSKMAP00000024095	Fucosyltransferase 9a.	Uncharacterized protein.	0.909
LOC108233304	LOC108250944	ENSKMAP00000015697	ENSKMAP00000005046	Fucosyltransferase 9a.	Uncharacterized protein.	0.909

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

50

average node degree:

9.09

avg. local clustering coefficient:

0.949

expected number of edges:

12

PPI enrichment p-value:

1.11e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051123

RNA polymerase II preinitiation complex assembly

8 of 18

2.92

9.32

1.35e-18

GO:0006367

Transcription initiation from RNA polymerase II promoter

9 of 34

2.7

9.28

2.13e-19

GO:0006352

DNA-templated transcription, initiation

10 of 81

2.36

8.24

2.13e-19

GO:0042789

mRNA transcription by RNA polymerase II

8 of 41

2.56

7.65

2.33e-16

GO:0060261

Positive regulation of transcription initiation from RNA polymerase II promoter

8 of 46

2.51

7.42

4.48e-16

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016251

RNA polymerase II general transcription initiation factor activity

5 of 25

2.57

4.39

3.55e-09

GO:0140296

General transcription initiation factor binding

5 of 54

2.24

3.54

6.18e-08

GO:0017025

TBP-class protein binding

4 of 28

2.43

3.15

8.77e-07

GO:0046982

Protein heterodimerization activity

8 of 334

1.65

2.94

2.81e-09

GO:0008134

Transcription factor binding

8 of 636

1.37

1.99

8.87e-08

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005669

Transcription factor TFIID complex

10 of 29

2.81

11.72

3.14e-24

GO:0033276

Transcription factor TFTC complex

6 of 14

2.9

7.14

3.19e-14

GO:0070461

SAGA-type complex

7 of 37

2.55

6.95

8.57e-15

GO:0000124

SAGA complex

4 of 23

2.51

3.73

6.89e-08

GO:0071339

MLL1 complex

4 of 34

2.34

3.35

2.61e-07

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4168

RNA polymerase II preinitiation complex assembly

9 of 10

3.23

12.24

1.25e-23

CL:4125

Transcription factor TFIID complex, and Transcription factor TFIIH holo complex

10 of 34

2.74

11.2

1.63e-23

CL:4172

SLIK (SAGA-like) complex, and Lateral mesoderm formation

5 of 5

3.27

6.35

2.44e-12

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

ccan03022

Basal transcription factors

9 of 34

2.7

9.97

5.56e-21

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-76042

RNA Polymerase II Transcription Initiation And Promoter Clearance

9 of 49

2.54

8.68

5.40e-19

MAP-75953

RNA Polymerase II Transcription Initiation

9 of 49

2.54

8.68

5.40e-19

MAP-73779

RNA Polymerase II Transcription Pre-Initiation And Promoter Opening

9 of 49

2.54

8.68

5.40e-19

MAP-73776

RNA Polymerase II Promoter Escape

9 of 49

2.54

8.68

5.40e-19

MAP-674695

RNA Polymerase II Pre-transcription Events

9 of 101

2.22

6.9

4.69e-17

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0016591

RNA polymerase II, holoenzyme

10 of 64

2.47

9.27

4.03e-21

GOCC:0070461

SAGA-type complex

7 of 34

2.59

7.03

7.63e-15

GOCC:0071339

MLL1 complex

4 of 26

2.46

3.55

1.37e-07

GOCC:0005654

Nucleoplasm

11 of 696

1.47

3.04

1.99e-14

GOCC:1990234

Transferase complex

11 of 858

1.38

2.6

1.71e-13

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0396

Initiation factor

4 of 59

2.1

2.46

1.07e-05

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