node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC108235979 | LOC108236971 | ENSKMAP00000010952 | ENSKMAP00000008766 | High mobility group box 1b. | High mobility group box 1a. | 0.901 |
LOC108235979 | TP53 | ENSKMAP00000010952 | ENSKMAP00000018969 | High mobility group box 1b. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.617 |
LOC108235979 | actl6a | ENSKMAP00000010952 | ENSKMAP00000029790 | High mobility group box 1b. | Actin-like 6A; Belongs to the actin family. | 0.607 |
LOC108235979 | actr5 | ENSKMAP00000010952 | ENSKMAP00000016359 | High mobility group box 1b. | Actin related protein 5; Belongs to the actin family. | 0.606 |
LOC108235979 | actr8 | ENSKMAP00000010952 | ENSKMAP00000015348 | High mobility group box 1b. | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. | 0.646 |
LOC108235979 | becn1 | ENSKMAP00000010952 | ENSKMAP00000025951 | High mobility group box 1b. | Beclin 1, autophagy related. | 0.930 |
LOC108235979 | ercc3 | ENSKMAP00000010952 | ENSKMAP00000029380 | High mobility group box 1b. | Excision repair cross-complementation group 3. | 0.598 |
LOC108235979 | gtf2h3 | ENSKMAP00000010952 | ENSKMAP00000026350 | High mobility group box 1b. | General transcription factor IIH, polypeptide 3. | 0.598 |
LOC108235979 | polrmt | ENSKMAP00000010952 | ENSKMAP00000005825 | High mobility group box 1b. | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. | 0.616 |
LOC108235979 | ruvbl1 | ENSKMAP00000010952 | ENSKMAP00000026792 | High mobility group box 1b. | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | 0.605 |
LOC108236971 | LOC108235979 | ENSKMAP00000008766 | ENSKMAP00000010952 | High mobility group box 1a. | High mobility group box 1b. | 0.901 |
LOC108236971 | TP53 | ENSKMAP00000008766 | ENSKMAP00000018969 | High mobility group box 1a. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.617 |
LOC108236971 | actl6a | ENSKMAP00000008766 | ENSKMAP00000029790 | High mobility group box 1a. | Actin-like 6A; Belongs to the actin family. | 0.607 |
LOC108236971 | actr5 | ENSKMAP00000008766 | ENSKMAP00000016359 | High mobility group box 1a. | Actin related protein 5; Belongs to the actin family. | 0.606 |
LOC108236971 | actr8 | ENSKMAP00000008766 | ENSKMAP00000015348 | High mobility group box 1a. | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. | 0.646 |
LOC108236971 | becn1 | ENSKMAP00000008766 | ENSKMAP00000025951 | High mobility group box 1a. | Beclin 1, autophagy related. | 0.930 |
LOC108236971 | ercc3 | ENSKMAP00000008766 | ENSKMAP00000029380 | High mobility group box 1a. | Excision repair cross-complementation group 3. | 0.598 |
LOC108236971 | gtf2h3 | ENSKMAP00000008766 | ENSKMAP00000026350 | High mobility group box 1a. | General transcription factor IIH, polypeptide 3. | 0.598 |
LOC108236971 | polrmt | ENSKMAP00000008766 | ENSKMAP00000005825 | High mobility group box 1a. | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. | 0.616 |
LOC108236971 | ruvbl1 | ENSKMAP00000008766 | ENSKMAP00000026792 | High mobility group box 1a. | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | 0.605 |