ptch2 protein (Kryptolebias marmoratus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

ptch2

Patched 2. (1488 aa)

Predicted Functional Partners:

smo

0.995

dhh

0.990

LOC108240386

0.984

boc

0.975

Gas1

0.973

ENSKMAP00000002396

0.972

LOC108236134

0.963

LOC108236247

0.963

SMURF2

0.963

shh

0.917

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSKMAP00000002396	Gas1	ENSKMAP00000002396	ENSKMAP00000008240	Uncharacterized protein.	Growth arrest-specific 1a.	0.906
ENSKMAP00000002396	LOC108240386	ENSKMAP00000002396	ENSKMAP00000027579	Uncharacterized protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.954
ENSKMAP00000002396	boc	ENSKMAP00000002396	ENSKMAP00000012760	Uncharacterized protein.	BOC cell adhesion associated, oncogene regulated.	0.935
ENSKMAP00000002396	dhh	ENSKMAP00000002396	ENSKMAP00000000197	Uncharacterized protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.953
ENSKMAP00000002396	ptch2	ENSKMAP00000002396	ENSKMAP00000014389	Uncharacterized protein.	Patched 2.	0.972
ENSKMAP00000002396	shh	ENSKMAP00000002396	ENSKMAP00000016956	Uncharacterized protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.560
ENSKMAP00000002396	smo	ENSKMAP00000002396	ENSKMAP00000020439	Uncharacterized protein.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.546
Gas1	ENSKMAP00000002396	ENSKMAP00000008240	ENSKMAP00000002396	Growth arrest-specific 1a.	Uncharacterized protein.	0.906
Gas1	LOC108240386	ENSKMAP00000008240	ENSKMAP00000027579	Growth arrest-specific 1a.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.952
Gas1	boc	ENSKMAP00000008240	ENSKMAP00000012760	Growth arrest-specific 1a.	BOC cell adhesion associated, oncogene regulated.	0.937
Gas1	dhh	ENSKMAP00000008240	ENSKMAP00000000197	Growth arrest-specific 1a.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.950
Gas1	ptch2	ENSKMAP00000008240	ENSKMAP00000014389	Growth arrest-specific 1a.	Patched 2.	0.973
Gas1	shh	ENSKMAP00000008240	ENSKMAP00000016956	Growth arrest-specific 1a.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.546
Gas1	smo	ENSKMAP00000008240	ENSKMAP00000020439	Growth arrest-specific 1a.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.497
LOC108236134	LOC108236247	ENSKMAP00000017281	ENSKMAP00000021672	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.901
LOC108236134	SMURF2	ENSKMAP00000017281	ENSKMAP00000022783	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.900
LOC108236134	ptch2	ENSKMAP00000017281	ENSKMAP00000014389	E3 ubiquitin-protein ligase.	Patched 2.	0.963
LOC108236247	LOC108236134	ENSKMAP00000021672	ENSKMAP00000017281	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.901
LOC108236247	SMURF2	ENSKMAP00000021672	ENSKMAP00000022783	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.901
LOC108236247	ptch2	ENSKMAP00000021672	ENSKMAP00000014389	E3 ubiquitin-protein ligase.	Patched 2.	0.963