STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psen2Presenilin 2. (352 aa)    
Predicted Functional Partners:
psenen
Presenilin enhancer, gamma-secretase subunit.
    
 0.967
NCSTN
Nicastrin.
   
 0.964
aph1a
APH1B gamma secretase subunit.
   
 0.960
APP
Amyloid beta precursor protein.
    
 
 0.719
LOC108232458
Amyloid beta (A4) precursor protein b.
    
 
 0.719
notch1
Notch receptor 1b.
    
 0.683
LOC108231024
Notch receptor 1a.
    
 0.683
park7
Parkinson protein 7.
      
 0.667
hypk
Huntingtin interacting protein K.
      
 0.667
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 
 0.665
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.