STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1841 aa)    
Predicted Functional Partners:
LOC108240703
Engulfment and cell motility 1.
    
 0.769
LOC108235659
Engulfment and cell motility 2.
    
 0.769
LOC108237558
Engulfment and cell motility 3.
    
 0.769
LOC108248149
V-crk avian sarcoma virus CT10 oncogene homolog.
    
 0.765
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.765
LOC108246548
CRK proto-oncogene, adaptor protein.
    
 0.765
LOC108251269
Cytochrome b-245, beta polypeptide (chronic granulomatous disease).
   
  
 0.684
tdo2
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
      
 0.675
nos1
Nitric oxide synthase; Produces nitric oxide (NO).
   
  
 0.674
LOC108250930
Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
      
 0.673
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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