hmgcl protein (Kryptolebias marmoratus) - STRING interaction network

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Score

hmgcl

3-hydroxy-3-methylglutaryl-CoA lyase. (338 aa)

Predicted Functional Partners:

LOC108242506

0.993

auh

0.978

oxct1

0.966

aacs

0.960

acaa1

0.950

hadhb

0.941

acat1

0.940

acat2

0.940

bdh1

0.939

acaa2

0.936

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108242506	aacs	ENSKMAP00000021391	ENSKMAP00000008824	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetoacetyl-CoA synthetase.	0.948
LOC108242506	acaa1	ENSKMAP00000021391	ENSKMAP00000012841	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.993
LOC108242506	acaa2	ENSKMAP00000021391	ENSKMAP00000004939	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.994
LOC108242506	acat1	ENSKMAP00000021391	ENSKMAP00000002715	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.994
LOC108242506	acat2	ENSKMAP00000021391	ENSKMAP00000021124	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.996
LOC108242506	auh	ENSKMAP00000021391	ENSKMAP00000015971	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	AU RNA binding protein/enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.955
LOC108242506	hadhb	ENSKMAP00000021391	ENSKMAP00000030027	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family.	0.995
LOC108242506	hmgcl	ENSKMAP00000021391	ENSKMAP00000018152	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxy-3-methylglutaryl-CoA lyase.	0.993
LOC108242506	oxct1	ENSKMAP00000021391	ENSKMAP00000018057	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.961
aacs	LOC108242506	ENSKMAP00000008824	ENSKMAP00000021391	Acetoacetyl-CoA synthetase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.948
aacs	acaa1	ENSKMAP00000008824	ENSKMAP00000012841	Acetoacetyl-CoA synthetase.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.596
aacs	acaa2	ENSKMAP00000008824	ENSKMAP00000004939	Acetoacetyl-CoA synthetase.	Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.596
aacs	acat1	ENSKMAP00000008824	ENSKMAP00000002715	Acetoacetyl-CoA synthetase.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.957
aacs	acat2	ENSKMAP00000008824	ENSKMAP00000021124	Acetoacetyl-CoA synthetase.	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.957
aacs	auh	ENSKMAP00000008824	ENSKMAP00000015971	Acetoacetyl-CoA synthetase.	AU RNA binding protein/enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.482
aacs	bdh1	ENSKMAP00000008824	ENSKMAP00000015484	Acetoacetyl-CoA synthetase.	3-hydroxybutyrate dehydrogenase, type 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.920
aacs	hadhb	ENSKMAP00000008824	ENSKMAP00000030027	Acetoacetyl-CoA synthetase.	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family.	0.641
aacs	hmgcl	ENSKMAP00000008824	ENSKMAP00000018152	Acetoacetyl-CoA synthetase.	3-hydroxy-3-methylglutaryl-CoA lyase.	0.960
aacs	oxct1	ENSKMAP00000008824	ENSKMAP00000018057	Acetoacetyl-CoA synthetase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.934
acaa1	LOC108242506	ENSKMAP00000012841	ENSKMAP00000021391	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.993