node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC108242425 | OGDH | ENSKMAP00000018749 | ENSKMAP00000028852 | Lipoyl-binding domain-containing protein. | Oxoglutarate dehydrogenase. | 0.998 |
LOC108242425 | bckdha | ENSKMAP00000018749 | ENSKMAP00000016875 | Lipoyl-binding domain-containing protein. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.958 |
LOC108242425 | bckdhb | ENSKMAP00000018749 | ENSKMAP00000004112 | Lipoyl-binding domain-containing protein. | Branched chain keto acid dehydrogenase E1 subunit beta. | 0.958 |
LOC108242425 | dhtkd1 | ENSKMAP00000018749 | ENSKMAP00000005266 | Lipoyl-binding domain-containing protein. | Dehydrogenase E1 and transketolase domain containing 1. | 0.996 |
LOC108242425 | dld | ENSKMAP00000018749 | ENSKMAP00000018385 | Lipoyl-binding domain-containing protein. | Dihydrolipoyl dehydrogenase. | 0.999 |
LOC108242425 | ogdh | ENSKMAP00000018749 | ENSKMAP00000022131 | Lipoyl-binding domain-containing protein. | Oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). | 0.998 |
LOC108242425 | pdhb | ENSKMAP00000018749 | ENSKMAP00000018436 | Lipoyl-binding domain-containing protein. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.968 |
LOC108242425 | sucla2 | ENSKMAP00000018749 | ENSKMAP00000007198 | Lipoyl-binding domain-containing protein. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.983 |
LOC108242425 | suclg1 | ENSKMAP00000018749 | ENSKMAP00000000125 | Lipoyl-binding domain-containing protein. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.992 |
LOC108242425 | suclg2 | ENSKMAP00000018749 | ENSKMAP00000011873 | Lipoyl-binding domain-containing protein. | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.974 |
OGDH | LOC108242425 | ENSKMAP00000028852 | ENSKMAP00000018749 | Oxoglutarate dehydrogenase. | Lipoyl-binding domain-containing protein. | 0.998 |
OGDH | bckdha | ENSKMAP00000028852 | ENSKMAP00000016875 | Oxoglutarate dehydrogenase. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.759 |
OGDH | bckdhb | ENSKMAP00000028852 | ENSKMAP00000004112 | Oxoglutarate dehydrogenase. | Branched chain keto acid dehydrogenase E1 subunit beta. | 0.776 |
OGDH | dhtkd1 | ENSKMAP00000028852 | ENSKMAP00000005266 | Oxoglutarate dehydrogenase. | Dehydrogenase E1 and transketolase domain containing 1. | 0.647 |
OGDH | dld | ENSKMAP00000028852 | ENSKMAP00000018385 | Oxoglutarate dehydrogenase. | Dihydrolipoyl dehydrogenase. | 0.998 |
OGDH | ogdh | ENSKMAP00000028852 | ENSKMAP00000022131 | Oxoglutarate dehydrogenase. | Oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). | 0.900 |
OGDH | pdhb | ENSKMAP00000028852 | ENSKMAP00000018436 | Oxoglutarate dehydrogenase. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.863 |
OGDH | sucla2 | ENSKMAP00000028852 | ENSKMAP00000007198 | Oxoglutarate dehydrogenase. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.923 |
OGDH | suclg1 | ENSKMAP00000028852 | ENSKMAP00000000125 | Oxoglutarate dehydrogenase. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.981 |
OGDH | suclg2 | ENSKMAP00000028852 | ENSKMAP00000011873 | Oxoglutarate dehydrogenase. | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.838 |