STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIEZO2Piezo-type mechanosensitive ion channel component. (2983 aa)    
Predicted Functional Partners:
mcm4
DNA helicase; Belongs to the MCM family.
   
 0.793
wdhd1
WD repeat and HMG-box DNA binding protein 1.
   
 
 0.775
tipin
TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.
   
 
 0.768
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae).
    
 0.754
timeless
Timeless circadian clock.
    
 
 0.748
LOC108248076
Checkpoint kinase 2.
    
 
 0.730
ENSKMAP00000001053
Uncharacterized protein.
   
 
 0.688
cdc6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.688
mcm9
Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family.
   
 0.676
mcm2
DNA helicase; Belongs to the MCM family.
   
 0.676
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.