asmt protein (Kryptolebias marmoratus) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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[Homology]

Score

asmt

Acetylserotonin O-methyltransferase. (357 aa)

Predicted Functional Partners:

AANAT

0.967

LOC108236158

0.962

LOC108243703

0.949

LOC108243353

0.909

LOC108247157

0.909

aldh9a1

0.908

LOC108238305

0.908

aldh2

0.908

aldh16a1

0.908

LOC108239348

0.907

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AANAT	LOC108236158	ENSKMAP00000015630	ENSKMAP00000017445	Arylalkylamine N-acetyltransferase 1.	N-acetyltransferase domain-containing protein.	0.901
AANAT	LOC108243703	ENSKMAP00000015630	ENSKMAP00000025048	Arylalkylamine N-acetyltransferase 1.	Arylalkylamine N-acetyltransferase 2.	0.901
AANAT	asmt	ENSKMAP00000015630	ENSKMAP00000028672	Arylalkylamine N-acetyltransferase 1.	Acetylserotonin O-methyltransferase.	0.967
LOC108236158	AANAT	ENSKMAP00000017445	ENSKMAP00000015630	N-acetyltransferase domain-containing protein.	Arylalkylamine N-acetyltransferase 1.	0.901
LOC108236158	LOC108243703	ENSKMAP00000017445	ENSKMAP00000025048	N-acetyltransferase domain-containing protein.	Arylalkylamine N-acetyltransferase 2.	0.902
LOC108236158	asmt	ENSKMAP00000017445	ENSKMAP00000028672	N-acetyltransferase domain-containing protein.	Acetylserotonin O-methyltransferase.	0.962
LOC108238305	aldh9a1	ENSKMAP00000007322	ENSKMAP00000005604	Aldehyde dehydrogenase 9 family, member A1b; Belongs to the aldehyde dehydrogenase family.	Aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1; Belongs to the aldehyde dehydrogenase family.	0.901
LOC108238305	asmt	ENSKMAP00000007322	ENSKMAP00000028672	Aldehyde dehydrogenase 9 family, member A1b; Belongs to the aldehyde dehydrogenase family.	Acetylserotonin O-methyltransferase.	0.908
LOC108239348	asmt	ENSKMAP00000003153	ENSKMAP00000028672	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Acetylserotonin O-methyltransferase.	0.907
LOC108243353	LOC108247157	ENSKMAP00000002732	ENSKMAP00000021533	Cytochrome P450, family 1, subfamily A; Belongs to the cytochrome P450 family.	Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.	0.927
LOC108243353	asmt	ENSKMAP00000002732	ENSKMAP00000028672	Cytochrome P450, family 1, subfamily A; Belongs to the cytochrome P450 family.	Acetylserotonin O-methyltransferase.	0.909
LOC108243703	AANAT	ENSKMAP00000025048	ENSKMAP00000015630	Arylalkylamine N-acetyltransferase 2.	Arylalkylamine N-acetyltransferase 1.	0.901
LOC108243703	LOC108236158	ENSKMAP00000025048	ENSKMAP00000017445	Arylalkylamine N-acetyltransferase 2.	N-acetyltransferase domain-containing protein.	0.902
LOC108243703	asmt	ENSKMAP00000025048	ENSKMAP00000028672	Arylalkylamine N-acetyltransferase 2.	Acetylserotonin O-methyltransferase.	0.949
LOC108247157	LOC108243353	ENSKMAP00000021533	ENSKMAP00000002732	Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.	Cytochrome P450, family 1, subfamily A; Belongs to the cytochrome P450 family.	0.927
LOC108247157	asmt	ENSKMAP00000021533	ENSKMAP00000028672	Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.	Acetylserotonin O-methyltransferase.	0.909
aldh16a1	asmt	ENSKMAP00000025983	ENSKMAP00000028672	Aldehyde dehydrogenase 16 family, member A1.	Acetylserotonin O-methyltransferase.	0.908
aldh2	asmt	ENSKMAP00000020531	ENSKMAP00000028672	Aldehyde dehydrogenase 2 family member, tandem duplicate 2; Belongs to the aldehyde dehydrogenase family.	Acetylserotonin O-methyltransferase.	0.908
aldh9a1	LOC108238305	ENSKMAP00000005604	ENSKMAP00000007322	Aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1; Belongs to the aldehyde dehydrogenase family.	Aldehyde dehydrogenase 9 family, member A1b; Belongs to the aldehyde dehydrogenase family.	0.901
aldh9a1	asmt	ENSKMAP00000005604	ENSKMAP00000028672	Aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1; Belongs to the aldehyde dehydrogenase family.	Acetylserotonin O-methyltransferase.	0.908

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Network Stats

number of nodes:

11

number of edges:

29

average node degree:

5.27

avg. local clustering coefficient:

0.778

expected number of edges:

15

PPI enrichment p-value:

0.00119

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006188

IMP biosynthetic process

4 of 12

1.55

1.06

0.0049

GO:0006189

De novo IMP biosynthetic process

3 of 11

1.46

0.93

0.0090

GO:0072522

Purine-containing compound biosynthetic process

5 of 33

1.21

0.88

0.0049

GO:1901137

Carbohydrate derivative biosynthetic process

5 of 55

0.99

0.71

0.0062

GO:0034654

Nucleobase-containing compound biosynthetic process

5 of 77

0.84

0.55

0.0141

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:592

Mixed, incl. RNA binding, and IMP biosynthesis enzyme PurP

3 of 8

1.6

0.87

0.0165

CL:725

Nucleoside monophosphate biosynthetic process

3 of 22

1.16

0.57

0.0479

CL:641

Cellular amino acid biosynthetic process, and Nucleoside monophosphate biosynthetic process

5 of 78

0.84

0.51

0.0232

CL:639

Small molecule metabolic process, and Pentose phosphate pathway

7 of 136

0.74

0.48

0.0165

CL:640

Biosynthesis of amino acids, and Nucleotide biosynthetic process

6 of 118

0.73

0.47

0.0203

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00230

Purine metabolism

5 of 33

1.21

1.06

0.00083

map01110

Biosynthesis of secondary metabolites

8 of 166

0.71

0.58

0.00083

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